1-(3-(Trifluoromethyl)benzyl)-5-(3-(trifluoromethyl)phenyl)-1H-1,2,3,4-tetraazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(3-(Trifluoromethyl)benzyl)-5-(3-(trifluoromethyl)phenyl)-1H-1,2,3,4-tetraazole
• 英文别名: 5-[3-(trifluoromethyl)phenyl]-1-[[3-(trifluoromethyl)phenyl]methyl]tetrazole
• 化学式: C₁₆H₁₀F₆N₄
• 分子量: 372.27
• InChiKey: PXSWXNAIERZUAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  43.6
• 氢给体数：
  0
• 氢受体数：
  9

文献信息

• REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：EP1438973A1

  公开（公告）日：2004-07-21

  A pharmaceutical composition for the prophylaxis and/or treatment of diseases induced, exacerbated or reignited by stressors comprising the compound of formula (I) wherein all symbols have the same meanings as described in the specification, etc. as an active ingredient.

  一种用于预防和/或治疗由应激源诱发、加重或复燃的疾病的药物组合物，由式 (I) 化合物组成 其中所有符号的含义与说明书中所述的相同等作为活性成分。
• Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
  申请人：Seko Takuya

  公开号：US20050009812A1

  公开（公告）日：2005-01-13

  A pharmaceutical composition for the prophylaxis and/or treatment of diseases induced, exacerbated or reignited by stressors comprising the compound of formula (I) wherein all symbols have the same meanings as described in the specification, etc. as an active ingredient.
• [EN] CATIONIC OLIGOMER OF A SACCHARIDE FOR RESOLVING ENANTIOMERS AND ASYMMETRIC SYNTHESIS<br/>[FR] OLIGOMERE CATIONIQUE DE SACCHARIDE POUR LA RESOLUTION D'ENANTIOMERES ET SYNTHESE ASYMETRIQUE
  申请人：UNIV SINGAPORE

  公开号：WO2005056609A1

  公开（公告）日：2005-06-23

  A cationic oligomer of a saccharide, wherein the saccharide is functionalized by a cationic group, for example an ammonium, phosphonium, imidazolium, or pyridinium group. In a preferred embodiment, the cationic oligomer of a saccharide is a cationic cyclodextrin. There is also provided a use of the cationic oligomer of a saccharide as a chiral agent for resolving enantiomers by a chromatographic method or an asymmetric synthesis.