2-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-5-[(2-methylprop-2-en-1-yl)oxy]phenol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-5-[(2-methylprop-2-en-1-yl)oxy]phenol
• 英文别名: 2-[4-(3,4-dimethoxyphenyl)-5-methyl-1H-pyrazol-3-yl]-5-(2-methylprop-2-enoxy)phenol
• 化学式: C₂₂H₂₄N₂O₄
• 分子量: 380.4
• InChiKey: MTVAPLLKMKQKPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  76.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• PEPTIDES, ESPECIALLY POLYPEPTIDES, PHAGE DISPLAY SCREENING METHOD AND ASSOCIATED MEANS, AND THEIR USES FOR RESEARCH AND BIOMEDICAL APPLICATIONS
  申请人：Institut National de la Santé Et de la Recherche Médicale

  公开号：EP3612552A1

  公开（公告）日：2020-02-26
• [EN] PEPTIDES, ESPECIALLY POLYPEPTIDES, PHAGE DISPLAY SCREENING METHOD AND ASSOCIATED MEANS, AND THEIR USES FOR RESEARCH AND BIOMEDICAL APPLICATIONS<br/>[FR] PEPTIDES, EN PARTICULIER POLYPEPTIDES, PROCÉDÉ DE CRIBLAGE D'EXPOSITION SUR PHAGES, MOYENS ASSOCIÉS ET LEURS UTILISATIONS POUR DES APPLICATIONS DE RECHERCHE ET BIOMÉDICALES
  申请人：INST NAT SANTE RECH MED

  公开号：WO2018192719A1

  公开（公告）日：2018-10-25

  The invention relates to peptides, hosts expressing such peptides and a process for producing and screening such peptides or hosts. The invention also relates to use of the peptide or host expressing such peptide in the detection of disease, to a method for constructing a library of hosts, in particular of phages expressing peptides. The invention also relates to a library of hosts expressing peptides and its use for example for detecting molecules and/or cells in a sample, in the treatment of disease. The present invention finds application in the therapeutic and diagnostic medical technical fields.