5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
• 化学式: C₂₁H₂₀O₁₀
• 分子量: 432.4
• InChiKey: SOSLMHZOJATCCP-MKZKRIRRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  166
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• [EN] COMPOSITION FOR BLOCKING UV RAYS OR REDUCING SKIN WRINKLES COMPRISING AFZELIN AS ACTIVE INGREDIENT<br/>[FR] COMPOSITION PERMETTANT DE BLOQUER LES RAYONS ULTRAVIOLETS OU DE RÉDUIRE LES RIDES DE LA PEAU COMPRENANT DE L'AFZÉLINE EN TANT QU'INGRÉDIENT ACTIF
  申请人：BIO SPECTRUM INC

  公开号：WO2014034977A1

  公开（公告）日：2014-03-06

  The present invention relates to a cosmetic composition for blocking UV rays or reducing skin wrinkles, which contains afzelin as an active ingredient. The invention also relates to a pharmaceutical or food composition for reducing skin wrinkles, which contains afzelin as an active ingredient. The composition of the invention has an excellent effect of reducing wrinkles by absorbing UVA and UVB to prevent UV rays from penetrating the skin, increasing collagen synthesis and inhibiting collagenase activity. In addition, because the composition of the invention is derived from natural materials, it is harmless to the human body and can be safely applied to cosmetic, pharmaceutical and food compositions.