[3-(5-Methyltetrazol-2-yl)-1-adamantyl]methanol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: [3-(5-Methyltetrazol-2-yl)-1-adamantyl]methanol
• 英文别名: [3-(5-methyltetrazol-2-yl)-1-adamantyl]methanol
• 化学式: C₁₃H₂₀N₄O
• 分子量: 248.32
• InChiKey: IGZWDTLFWDHYOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  63.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• DEUTERATED AMINOGLYCIDAL COMPOUNDS
  申请人：Gant Thomas G.

  公开号：US20090182057A1

  公开（公告）日：2009-07-16

  Provided herein are substituted aminoglycidyl compounds of Formula (1), processes of preparation, and pharmaceutical compositions thereof and methods of their use for treating, preventing, or ameliorating one or more symptoms of a social anxiety disorder, an anxiety disorder, hyperthyroidism, tremor, glaucoma, hypertension, coronary artery bypass graft, chronic stable angina, atrial arrhythmia, migraine, bleeding esophageal varices, hypertrophic subaortic stenosis, heart failure, post-myocardial infarction, decreased left ventricular function after recent myocardial infarction, and/or any disorder ameliorated by beta adrenergic receptor modulators.

  本文提供了一种式子为（1）的取代氨基环氧丙烷化合物，其制备方法，以及其制药组合物和用于治疗、预防或缓解社交焦虑症、焦虑症、甲状腺功能亢进、震颤、青光眼、高血压、冠状动脉搭桥手术、慢性稳定型心绞痛、心房心动过速、偏头痛、食管静脉曲张出血、肥厚性主动脉瓣下狭窄、心力衰竭、心肌梗死后、近期心肌梗死后左心室功能下降和/或任何通过β肾上腺素能受体调节剂缓解的疾病的治疗方法。
• N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN
  申请人：Genentech, Inc.

  公开号：EP2855428A1

  公开（公告）日：2015-04-08
• [EN] N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN<br/>[FR] BENZAMIDES N-SUBSTITUÉS ET LEUR UTILISATION DANS LE TRAITEMENT DE LA DOULEUR
  申请人：GENENTECH INC

  公开号：WO2013177224A1

  公开（公告）日：2013-11-28

  The invention provides novel compounds having the general formula (I) and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X2, L, subscript m, X1, B, R1, R2, R3, R4, R5 and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.