N-[(E)-(3-methylcyclohexylidene)amino]-4-pentyl-1,3-thiazol-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-[(E)-(3-methylcyclohexylidene)amino]-4-pentyl-1,3-thiazol-2-amine
• 化学式: C₁₅H₂₅N₃S
• 分子量: 279.4
• InChiKey: DBKUYRFJICAABG-GHRIWEEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  65.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• EP2908827A1
  申请人：——

  公开号：EP2908827A1

  公开（公告）日：2015-08-26
• VITAMIN D ANALOGUES FOR THE TREATMENT OF A NEUROLOGICAL DISORDER
  申请人：CELUS PHARMACEUTICALS, INC.

  公开号：US20150246061A1

  公开（公告）日：2015-09-03

  Disclosed herein are methods that use a vitamin D analogue to treat a neurological disorder. Additionally, pharmaceutical compositions comprising a vitamin D analogue and a neurotherapeutic agent are disclosed, and methods of using the same. The pharmaceutical compositions and methods of the invention are useful for the treatment of a neurological disorder, for example, Alzheimer's disease, multiple sclerosis, Parkinson's disease, epilepsy, neuropathic pain, or other conditions that affect the central or peripheral nervous system of a subject.
• [EN] VITAMIN D ANALOGUES FOR THE TREATMENT OF A NEUROLOGICAL DISORDER<br/>[FR] UTILISATION D'ANALOGUES DE LA VITAMINE D POUR LE TRAITEMENT D'UNE AFFECTION NEUROLOGIQUE
  申请人：CELUS PHARMACEUTICALS INC

  公开号：WO2014063105A1

  公开（公告）日：2014-04-24

  Disclosed herein are methods that use a vitamin D analogue to treat a neurological disorder. Additionally, pharmaceutical compositions comprising a vitamin D analogue and a neurotherapeutic agent are disclosed, and methods of using the same. The pharmaceutical compositions and methods of the invention are useful for the treatment of a neurological disorder, for example, Alzheimer's disease, multiple sclerosis, Parkinson's disease, epilepsy, neuropathic pain, or other conditions that affect the central or peripheral nervous system of a subject.