2,4,5-tris[4-(fluoromethyl)phenyl]-1H-imidazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2,4,5-tris[4-(fluoromethyl)phenyl]-1H-imidazole
• 化学式: C₂₄H₁₉F₃N₂
• 分子量: 392.4
• InChiKey: CHJNYJLBRQSMKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Methods and compositions for treating mucusal tissue disorders
  申请人：The University of North Carolina at Chapel Hill

  公开号：US10406200B2

  公开（公告）日：2019-09-10

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.

  本发明提供了包含谷胱甘肽（含或不含硫氰酸盐）的组合物和制剂及其用于治疗粘膜/上皮组织疾病和失调的方法。
• Methods and compositions for treating mucosal tissue disorders
  申请人：The University of North Carolina at Chapel Hill

  公开号：US11058743B2

  公开（公告）日：2021-07-13

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.

  本发明提供了包含谷胱甘肽（含或不含硫氰酸盐）的组合物和制剂及其用于治疗粘膜/上皮组织疾病和失调的方法。
• Methods and Compositions for Treating Mucosal Tissue Disorders
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20150010654A1

  公开（公告）日：2015-01-08

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
• METHODS AND COMPOSITIONS FOR TREATING MUCUSAL TISSUE DISORDERS
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20160228490A1

  公开（公告）日：2016-08-11

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
• METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20200179478A1

  公开（公告）日：2020-06-11

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.