[(2R,3R)-2-[8-[(3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-1,2,3,4-tetrahydronaphthalen-2-yl]-3,4,6-trihydroxy-5-oxobenzo[7]annulen-1-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 1-[(2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,6-trihydroxy-5-oxobenzo[7]annulene-8-carboxylate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: [(2R,3R)-2-[8-[(3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-1,2,3,4-tetrahydronaphthalen-2-yl]-3,4,6-trihydroxy-5-oxobenzo[7]annulen-1-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 1-[(2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,6-trihydroxy-5-oxobenzo[7]annulene-8-carboxylate
• 化学式: C₆₅H₄₈O₂₈
• 分子量: 1277.1
• InChiKey: LKNWJYYHYSFKNJ-BVWWTFGRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  93
• 可旋转键数：
  12
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  496
• 氢给体数：
  18
• 氢受体数：
  28

文献信息

• ANTI-OBESITY AGENT COMPRISING COMPOUND CONTAINING BENZOTROPOLONE RING
  申请人：SUNTORY HOLDINGS LIMITED

  公开号：US20140121388A1

  公开（公告）日：2014-05-01

  The object of the present invention is to provide an anti-obesity agent which contains a tea-derived component and which is safe and does not compromise the flavor of foods and beverages. According to the present invention, a safe and palatable anti-obesity agent can be provided by incorporating a benzotropolone ring-containing compound which has tea-derived, high inhibitory activities against lipase and alfa-glucosidase. The anti-obesity agent of the present invention does not compromise the flavor of foods and beverage, has palatability, and can be used in various use applications including foods and beverages intended for health enhancement such as reduction in triglycerides.

  本发明的目的是提供一种抗肥胖剂，其含有茶叶成分，安全且不影响食物和饮料的口味。根据本发明，通过将含有苯并环己酮环的化合物纳入其中，可提供一种安全且可口的抗肥胖剂，该化合物具有茶叶衍生的高抑制脂肪酶和阿尔法-葡萄糖苷酶的活性。本发明的抗肥胖剂不会影响食物和饮料的口味，具有可口性，并可用于各种用途，包括旨在提高健康的食品和饮料，如降低三酰甘油。