2-benzyloxy-2'-hydroxy-4',6'-diisopropyloxy-4,5'-dimethoxychalcone | 1026551-54-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 2-benzyloxy-2'-hydroxy-4',6'-diisopropyloxy-4,5'-dimethoxychalcone
• 英文别名: (E)-1-[6-hydroxy-3-methoxy-2,4-di(propan-2-yloxy)phenyl]-3-(4-methoxy-2-phenylmethoxyphenyl)prop-2-en-1-one
• CAS: 1026551-54-1
• 化学式: C₃₀H₃₄O₇
• 分子量: 506.596
• InChiKey: WHBAZCXQGAHPNO-FYWRMAATSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  37
• 可旋转键数：
  12
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  83.4
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-benzyloxy-2'-hydroxy-4',6'-diisopropyloxy-4,5'-dimethoxychalcone 在 selenium(IV) oxide 作用下， 以 戊醇 为溶剂， 反应 24.0h， 以0.28 g的产率得到5,7-diisopropyloxy-6-methoxy-2-(2-benzyloxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
  参考文献：
  名称：

  Synthesis of 5,7-Dihydroxy-6-methoxy-2-(2-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one and Reassignment of Structure of Tamaridone¹

  摘要：

  The proposed structure of a new flavone, tamaridone, isolated from Tamarix dioica Roxb is untenable on the basis of comparison with its synthetic sample. Its structure has been now revised to 5,7-dihydroxy-8-methoxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one by careful spectral studies.

  DOI：

  10.1080/00397919708006071
• 作为产物：
  描述：

  2-羟基-5-[2-(三甲基甲硅烷基)乙炔]-苯羧酸甲酯 、 1-(6-羟基-2,4-二异丙氧基-3-甲氧基苯基)乙酮 在 氢氧化钾 作用下， 以 乙醇 、 水 为溶剂， 反应 48.0h， 以1.2 g的产率得到2-benzyloxy-2'-hydroxy-4',6'-diisopropyloxy-4,5'-dimethoxychalcone
  参考文献：
  名称：

  Synthesis of 5,7-Dihydroxy-6-methoxy-2-(2-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one and Reassignment of Structure of Tamaridone¹

  摘要：

  The proposed structure of a new flavone, tamaridone, isolated from Tamarix dioica Roxb is untenable on the basis of comparison with its synthetic sample. Its structure has been now revised to 5,7-dihydroxy-8-methoxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one by careful spectral studies.

  DOI：

  10.1080/00397919708006071

文献信息

• Synthesis of 5,7-Dihydroxy-6-methoxy-2-(2-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one and Reassignment of Structure of Tamaridone¹
  作者：Subhash C Jain、Vivek K Rajwanshi、Ravindra Kumar、Sangeeta Talwar、Aparna Bharadvaja

  DOI：10.1080/00397919708006071

  日期：1997.4

  The proposed structure of a new flavone, tamaridone, isolated from Tamarix dioica Roxb is untenable on the basis of comparison with its synthetic sample. Its structure has been now revised to 5,7-dihydroxy-8-methoxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one by careful spectral studies.