4-Chloro-1-(chloromethyl)-5-methyl-2-phenylpyrazol-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-Chloro-1-(chloromethyl)-5-methyl-2-phenylpyrazol-3-one
• 英文别名: 4-chloro-1-(chloromethyl)-5-methyl-2-phenylpyrazol-3-one
• 化学式: C₁₁H₁₀Cl₂N₂O
• 分子量: 257.11
• InChiKey: WQDPDHLKFTWBMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• X-RAY CONTRAST MEDIA COMPOSITIONS AND METHODS OF USING THE SAME TO TREAT INFLAMMATION ASSOCIATED CONDITIONS
  申请人：3E Therapeutics Corporation

  公开号：EP2916831A1

  公开（公告）日：2015-09-16
• X-RAY CONTRAST MEDIA COMPOSITIONS AND METHODS OF USING THE SAME TO TREAT, REDUCE OR DELAY THE ONSET OF CNS INFLAMMATION AND INFLAMMATION ASSOCIATED CONDITIONS
  申请人：LASSER Elliott C.

  公开号：US20150290158A1

  公开（公告）日：2015-10-15

  Embodiments disclosed herein relate to improved X-ray contrast media compositions and methods of using the same for treating symptoms related to allergic reactions, inflammatory conditions, symptoms of the common cold and certain cancers.
• X-RAY CONTRAST MEDIA COMPOSITIONS AND METHODS OF USING THE SAME TO TREAT, REDUCE OR DELAY THE ONSET OF MIGRAINE
  申请人：3E THERAPEUTICS CORPORATION

  公开号：US20180360784A1

  公开（公告）日：2018-12-20

  Embodiments disclosed herein relate to improved X-ray contrast media compositions and methods of using the same for treating symptoms related to allergic reactions, inflammatory conditions, symptoms of the common cold and certain cancers.
• [EN] X-RAY CONTRAST MEDIA COMPOSITIONS AND METHODS OF USING THE SAME TO TREAT INFLAMMATION ASSOCIATED CONDITIONS<br/>[FR] COMPOSITIONS DE MILIEU DE CONTRASTE POUR RADIOGRAPHIE ET LEURS PROCÉDÉS D'UTILISATION POUR TRAITER UNE INFLAMMATION ET DES ÉTATS ASSOCIÉS À UNE INFLAMMATION.
  申请人：LASSER ELLIOTT C

  公开号：WO2014074744A1

  公开（公告）日：2014-05-15

  Embodiments disclosed herein relate to improved X-ray contrast media compositions and methods of using the same for treating symptoms related to allergic reactions, inflammatory conditions, symptoms of the common cold and certain cancers.