2-[3-(Dimethylamino)propyl]-1-ethyltetrazole-5-thione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-[3-(Dimethylamino)propyl]-1-ethyltetrazole-5-thione
• 英文别名: 2-[3-(dimethylamino)propyl]-1-ethyltetrazole-5-thione
• 化学式: C₈H₁₇N₅S
• 分子量: 215.32
• InChiKey: UIGCARDEBUVKTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  66.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• SUBSTRATES, SYSTEMS, AND METHODS FOR ARRAY SYNTHESIS AND BIOMOLECULAR ANALYSIS
  申请人：Vibrant Holdings, LLC

  公开号：EP2920272A2

  公开（公告）日：2015-09-23
• SELECTIVE PHOTO ACTIVATION OF AMINO ACIDS FOR SINGLE STEP PEPTIDE COUPLING
  申请人：Vibrant Holdings, LLC

  公开号：EP3107926A1

  公开（公告）日：2016-12-28
• [EN] SUBSTRATES, SYSTEMS, AND METHODS FOR ARRAY SYNTHESIS AND BIOMOLECULAR ANALYSIS<br/>[FR] SUBSTRATS, SYSTÈMES ET PROCÉDÉS POUR LA SYNTHÈSE DE RÉSEAU ET L'ANALYSE BIOMOLÉCULAIRE
  申请人：VIBRANT HOLDINGS LLC

  公开号：WO2014078606A2

  公开（公告）日：2014-05-22

  Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N->C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
• [EN] SELECTIVE PHOTO ACTIVATION OF AMINO ACIDS FOR SINGLE STEP PEPTIDE COUPLING<br/>[FR] PHOTO-ACTIVATION SÉLECTIVE D'ACIDES AMINÉS POUR UN COUPLAGE PEPTIDIQUE EN UNE SEULE ÉTAPE
  申请人：VIBRANT HOLDINGS LLC

  公开号：WO2015127409A1

  公开（公告）日：2015-08-27

  Disclosed herein are formulations, substrates, and arrays for amino acid and peptide synthesis on microarrays. In certain embodiments, methods for manufacturing and using the formulations, substrates, and arrays including one-step coupling, e.g., for synthesis of peptides in a C→N orientation are disclosed. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.