7-(Hydroxymethyl)-5-methoxy-2-phenylchromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 7-(Hydroxymethyl)-5-methoxy-2-phenylchromen-4-one
• 英文别名: 7-(hydroxymethyl)-5-methoxy-2-phenylchromen-4-one
• 化学式: C₁₇H₁₄O₄
• 分子量: 282.29
• InChiKey: FEDKXGNDNDCWCX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• NOVEL USE OF FLAVONE-BASED COMPOUND
  申请人：Industry-Academic Cooperation Foundation, Younsei University

  公开号：US20140148504A1

  公开（公告）日：2014-05-29

  The present invention relates to a novel use of a flavone-based compound or a Kaempferia parviflora extract comprising the same. More particularly, the present invention relates to a composition for wrinkle improvement, anti-aging and skin elasticity enhancement or a composition for skin moisturization, which comprises a flavone-based compound or a Kaempferia parviflora extract comprising the same as an active ingredient. The composition of the present invention is very effective in inhibiting the activity of Collagenase-1 (MMP-1) and promoting the synthesis of collagen. Therefore, the composition of the present invention is useful for wrinkle improvement, anti-aging, skin elasticity enhancement, and skin moisturization via the inhibition of moisture loss from the skin.
• USE OF KAEMPFERIA PARVIFLORA WALL. EX. BAKER EXTRACTS OR FLAVONE COMPOUND FOR PREVENTING OR TREATING MUSCLE DISEASES, OR IMPROVING MUSCLE FUNCTION
  申请人：INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

  公开号：US20150190452A1

  公开（公告）日：2015-07-09

  The present invention relates to a pharmaceutical composition containing Kaempferia parviflora Wall. Ex. Baker extracts for treating muscle diseases, and more specifically to a pharmaceutical composition containing, as an active ingredient, Kaempferia parviflora Wall. Ex. Baker extracts or flavone compound isolated therefrom for treating muscle diseases or a dietary composition for improving muscle function. Kaempferia parviflora Wall. Ex. Baker extracts or flavone compound isolated therefrom according to the present invention reduces protein catabolism in the muscles and increases muscle cell differentiation and anabolism, and is thus effective for preparing pharmaceutical composition for treating muscle diseases and dietary composition for improving muscle function.
• US9669066B2
  申请人：——

  公开号：US9669066B2

  公开（公告）日：2017-06-06