E-trimethylsilylmethyl-3 pentadiene-1,3 | 100580-64-1

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物
• 英文名称: E-trimethylsilylmethyl-3 pentadiene-1,3
• 英文别名: trimethyl-[(E)-2-methylidenepent-3-enyl]silane
• CAS: 100580-64-1
• 化学式: C₉H₁₈Si
• 分子量: 154.327
• InChiKey: JSFIRLZMLPNJTJ-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.46
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  反-1-溴-1-丙烯 、 10-(1-Trimethylsilanylmethyl-vinyl)-9-oxa-10-bora-bicyclo[3.3.2]decane 在 四(三苯基膦)钯 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 以63%的产率得到E-trimethylsilylmethyl-3 pentadiene-1,3
  参考文献：
  名称：

  MARKOVNIKOV VINYLBORINATES FROM 9-OXA-10-BORABICYCLO[3.3.2]DECANES

  摘要：

  Alkylborinates 1 react with alpha-methoxyvinyllithium (LiAMV) to produce stable ''ate'' complexes, 2, which undergo BCS-induced alkyl group migration providing new air-stable vinylborinates, 3. These intermediates which are readily converted to either unsymmetrical 1,1-disubstituted alkenes (7) via the Suzuki-Miyaura coupling or, oxidatively, to methyl ketones, (8), one of which was converted to the antihistaminic drug, metron S, 10. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01578-5

文献信息

• Synthése de triméthylsilylméthyl-2 diènes-1,3
  作者：Deriouche Djahanbini、Bernard Cazes、Jacques Gore、François Gobert

  DOI：10.1016/s0040-4020(01)96403-8

  日期：1985.1
• DJAHANBINI, D.;CAZES, B.;GORE, J.;GOBERT, F., TETRAHEDRON, 1985, 41, N 5, 867-873
  作者：DJAHANBINI, D.、CAZES, B.、GORE, J.、GOBERT, F.

  DOI：——

  日期：——
• MARKOVNIKOV VINYLBORINATES FROM 9-OXA-10-BORABICYCLO[3.3.2]DECANES
  作者：John A. Soderquist、Jorge Ramos、Karl Matos

  DOI：10.1016/s0040-4039(97)01578-5

  日期：1997.9

  Alkylborinates 1 react with alpha-methoxyvinyllithium (LiAMV) to produce stable ''ate'' complexes, 2, which undergo BCS-induced alkyl group migration providing new air-stable vinylborinates, 3. These intermediates which are readily converted to either unsymmetrical 1,1-disubstituted alkenes (7) via the Suzuki-Miyaura coupling or, oxidatively, to methyl ketones, (8), one of which was converted to the antihistaminic drug, metron S, 10. (C) 1997 Elsevier Science Ltd.