4,5-di(biphenyl-4-yl)-2,7-di-tert-butyl-9,9-dimethyl-9H-xanthene | 1332869-88-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 4,5-di(biphenyl-4-yl)-2,7-di-tert-butyl-9,9-dimethyl-9H-xanthene
• 英文别名: 2,7-Ditert-butyl-9,9-dimethyl-4,5-bis(4-phenylphenyl)xanthene；2,7-ditert-butyl-9,9-dimethyl-4,5-bis(4-phenylphenyl)xanthene
• CAS: 1332869-88-1
• 化学式: C₄₇H₄₆O
• 分子量: 626.882
• InChiKey: QVKAFBJSFIETCQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.2
• 重原子数：
  48
• 可旋转键数：
  6
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-联苯硼酸 在 palladium diacetate 、 2,2'-双(二苯基磷)联苯 、 copper(l) chloride 作用下， 以 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 22.0h， 生成 4,5-di(biphenyl-4-yl)-2,7-di-tert-butyl-9,9-dimethyl-9H-xanthene
  参考文献：
  名称：

  Double-coupling of dibromo arenes with aryltriolborates for synthesis of diaryl-substituted planar frameworks

  摘要：

  A new method for simple and practical synthesis of diaryl-substituted arenes using potassium aryltriolborates was developed. Double-cross-coupling of dibromo arenes with aryltriolborates was carried out in the presence of a palladium catalyst, such as Pd(OAc)(2), Pd(PPh3)(4) or Pd(OAc)(2)/BIPHEP. The use of CuCl (40 mol %) with a palladium catalyst was found to be highly effective to give diaryl-substituted aromatic compounds in good yields. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.06.083

文献信息

• Double-coupling of dibromo arenes with aryltriolborates for synthesis of diaryl-substituted planar frameworks
  作者：Gao-Qiang Li、Yasunori Yamamoto、Norio Miyaura

  DOI：10.1016/j.tet.2011.06.083

  日期：2011.9

  A new method for simple and practical synthesis of diaryl-substituted arenes using potassium aryltriolborates was developed. Double-cross-coupling of dibromo arenes with aryltriolborates was carried out in the presence of a palladium catalyst, such as Pd(OAc)(2), Pd(PPh3)(4) or Pd(OAc)(2)/BIPHEP. The use of CuCl (40 mol %) with a palladium catalyst was found to be highly effective to give diaryl-substituted aromatic compounds in good yields. (C) 2011 Elsevier Ltd. All rights reserved.