2-Methyl-5-(6-methylpyridin-2-yl)-1,3-thiazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-Methyl-5-(6-methylpyridin-2-yl)-1,3-thiazole
• 英文别名: 2-methyl-5-(6-methylpyridin-2-yl)-1,3-thiazole
• 化学式: C₁₀H₁₀N₂S
• 分子量: 190.27
• InChiKey: JWLFYXJJAMWRBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 6,11-BRIDGED BIARYL MACROLIDES
  申请人：Enanta Pharmaceuticals, Inc.

  公开号：US20140187780A1

  公开（公告）日：2014-07-03

  The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.