(1E,3S,5E)-1-(2-ethyl-1,3-thiazol-4-yl)-2-methyl-6-(trifluoromethyl)nona-1,5,8-trien-3-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (1E,3S,5E)-1-(2-ethyl-1,3-thiazol-4-yl)-2-methyl-6-(trifluoromethyl)nona-1,5,8-trien-3-ol
• 化学式: C₁₆H₂₀F₃NOS
• 分子量: 331.4
• InChiKey: FPYRBKHFYQKXIG-WRYMYNDYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  61.4
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF
  申请人：Sloan-Kettering Institute for Cancer Research

  公开号：US20140213618A1

  公开（公告）日：2014-07-31

  The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).