3,4-Ditert-butyl-1,5-dimethylpyrazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3,4-Ditert-butyl-1,5-dimethylpyrazole
• 英文别名: 3,4-ditert-butyl-1,5-dimethylpyrazole
• 化学式: C₁₃H₂₄N₂
• 分子量: 208.34
• InChiKey: AGYKSMDGGSDJME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS
  申请人：InterMune, Inc.

  公开号：US20140213538A1

  公开（公告）日：2014-07-31

  Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.

  本发明提供了化合物、制备这种化合物的方法、包含这种化合物的制药组合物和药物，以及使用这种化合物治疗、预防或诊断与一种或多种溶血磷脂酸受体相关的疾病、疾病、或病况的方法。
• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：UNIVERSAL DISPLAY CORPORATION

  公开号：US20220106343A1

  公开（公告）日：2022-04-07

  Provided are organometallic compounds including a ligand L A having a structure of Also provided are formulations comprising these organometallic compounds. Further provided are OLEDs and related consumer products that utilize these organometallic compounds.

  提供了包括配体LA在内的有机金属化合物，其结构为。还提供了含有这些有机金属化合物的配方。此外，还提供了利用这些有机金属化合物的OLED和相关消费品。
• MACROCYCLIC COMPOUNDS
  申请人：ZENO MANAGEMENT, INC.

  公开号：US20220144854A1

  公开（公告）日：2022-05-12

  Disclosed are macrocyclic compounds of formula (I) comprising a 2-carboxy indole ring. Such compounds, and their pharmaceutically acceptable salts, are useful as Mcl-1 (myeloid cell leukemia-1) inhibitors. The compounds may be used in treating a disease or condition, such as cancer.