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1-ethyl-5-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid | 1622077-68-2

中文名称
——
中文别名
——
英文名称
1-ethyl-5-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid
英文别名
2-Ethyl-3-phenyl-3,4-dihydropyrazole-5-carboxylic acid;2-ethyl-3-phenyl-3,4-dihydropyrazole-5-carboxylic acid
1-ethyl-5-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid化学式
CAS
1622077-68-2
化学式
C12H14N2O2
mdl
——
分子量
218.255
InChiKey
IOIGVJCQHJRAMC-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    1.8
  • 重原子数:
    16
  • 可旋转键数:
    3
  • 环数:
    2.0
  • sp3杂化的碳原子比例:
    0.33
  • 拓扑面积:
    52.9
  • 氢给体数:
    1
  • 氢受体数:
    4

文献信息

  • SUBSTITUTED PYRAZOLE AZETIDINES AS SPHINGOSINE RECEPTOR MODULATORS
    申请人:Allergan, Inc.
    公开号:US20140228345A1
    公开(公告)日:2014-08-14
    The present invention relates to substituted pyrazole azetidines, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    本发明涉及替代吡唑吖唑啉,制备它们的方法,含有它们的药物组合物以及它们作为调节鞘氨醇-1-磷酸受体的药物的用途。
  • SUBSTITUTED PYRAZOLES AS SPHINGOSINE RECEPTOR MODULATORS
    申请人:Allergan, Inc.
    公开号:US20140235587A1
    公开(公告)日:2014-08-21
    The present invention relates to substituted pyrazoles, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    本发明涉及取代的吡唑,其制备方法,含有它们的制药组合物以及它们作为调节鞘氨醇-1-磷酸受体的药物的用途。
  • US8987467B2
    申请人:——
    公开号:US8987467B2
    公开(公告)日:2015-03-24
  • [EN] SUBSTITUTED 4,5-DIHYDROPYRAZOLE-1,2,4-OXADIAZOLE DERIVATIVES AS SPHINGOSINE RECEPTOR MODULATORS<br/>[FR] DÉRIVÉS SUBSTITUÉS DE 4,5-DIHYDROPYRAZOLE-1,2,4-OXADIAZOLE EN TANT QUE MODULATEURS DES RÉCEPTEURS DE LA SPHINGOSINE
    申请人:ALLERGAN INC
    公开号:WO2014127149A1
    公开(公告)日:2014-08-21
    The present invention relates to substituted pyrazoles, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1- phosphate receptors. Claimed are compounds of Markush formula (I): [Formula should be inserted here] A typical example for a Markush formula (I) compound is example 7: Example 7 [Formula should be inserted here]
  • [EN] SUBSTITUTED PYRAZOLE AZETIDINES AS SPHINGOSINE RECEPTOR MODULATORS<br/>[FR] AZÉTIDINES DE PYRAZOLE SUBSTITUÉS UTILISÉS EN TANT QUE MODULATEURS DES RÉCEPTEUR DE SPHINGOSINE
    申请人:ALLERGAN INC
    公开号:WO2014127152A1
    公开(公告)日:2014-08-21
    The present invention relates to substituted pyrazole azetidines, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
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