N,N-di(2-ethylhexyl)butyramide | 112724-94-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N-di(2-ethylhexyl)butyramide
• 英文别名: Butanamide, N,N-bis(2-ethylhexyl)-；N,N-bis(2-ethylhexyl)butanamide
• CAS: 112724-94-4
• 化学式: C₂₀H₄₁NO
• 分子量: 311.552
• InChiKey: ZXHLGQVRYKTEHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  22
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  丁酰氯 、 二异辛胺 生成 N,N-di(2-ethylhexyl)butyramide
  参考文献：
  名称：

  MUSIKAS, CLAUDE;ZORZ, PHILIPPE

  摘要：

  DOI：

文献信息

• NOVEL DISSYMMETRIC N,N-DIALKYLAMIDES, THE SYNTHESIS THEREOF AND USES OF SAME
  申请人：COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

  公开号：US20180222849A1

  公开（公告）日：2018-08-09

  Novel dissymmetric N,N-dialkylamides which meet the following formula (I): where R represents a linear or branched alkyl group at C 8 to C 15 . A method for synthesizing these N,N-dialkylamides, and to the uses of same as extractants, alone or in admixture, in order to extract uranium and/or plutonium from an aqueous acid solution, or to totally or separate uranium from plutonium from an aqueous acid solution and, in particular, an aqueous solution resulting from dissolving spent nuclear fuel in nitric acid. Further, a method for processing an aqueous solution resulting from the dissolution of a spent nuclear fuel in nitric acid, allowing the uranium and plutonium contained in the solution to be extracted, separated and decontaminated in a single cycle, without requiring any plutonium reduction operation, and in which one of the aforementioned N,N-dialkylamides or a mixture of same is used as extractant. Applications for the method include the processing of spent nuclear fuels, in particular comprising uranium (e.g. UOX) or uranium and plutonium (e.g. MOX).

  新颖的不对称N,N-二烷基酰胺，符合以下公式(I)：其中R代表C8到C15的直链或支链烷基基团。一种合成这些N,N-二烷基酰胺的方法，以及将其作为萃取剂单独使用或与其他物质混合以从水酸性溶液中萃取铀和/或钚，或者从水酸性溶液中完全或分离铀和钚，特别是从用硝酸溶解废核燃料后得到的水酸性溶液。此外，提供一种处理用硝酸溶解废核燃料后得到的水溶液的方法，允许在单个循环中提取、分离和脱污该溶液中含有的铀和钚，无需进行任何钚还原操作，并且其中使用上述N,N-二烷基酰胺或其混合物之一作为萃取剂。该方法的应用包括处理废核燃料，特别是包含铀（如UOX）或铀和钚（如MOX）的废核燃料。
• DISSYMMETRIC N,N-DIALKYLAMIDES USED PARTICULARLY FOR SEPARATING URANIUM(VI) FROM PLUTONIUM(IV), SYNTHESIS THEREOF AND USES OF SAME
  申请人：COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÊNERGIES ALTERNATIVES

  公开号：US20210332002A1

  公开（公告）日：2021-10-28

  A dissymmetric RN,N-dialkylamides of formula (I) in which: R 1 represents a linear C 1 to C 4 alkyl, R 2 represents a linear C 1 to C 10 alkyl, and R 3 represents a linear or branched C 6 to C 15 alkyl, where R 3 is different from a n-octyl, n-decyl, n-dodecyl, 2-ethylhexyl and 2-ethyloctyl group when R 1 represents a n-butyl group and R 2 represents an ethyl group. A method for synthesising the N,N-dialkylamides, and uses of same for extracting uranium and/or plutonium from an aqueous acid solution or for fully or partially separating the uranium from the plutonium contained in an aqueous acid solution and a solution resulting from the dissolution of spent nuclear fuel in nitric acid. A method for treating an aqueous solution resulting from the dissolution of spent nuclear fuel in nitric acid, which allows the uranium and the plutonium contained in the solution to be extracted, separated and decontaminated in a single cycle.

  公式（I）中的非对称RN，N-二烷基酰胺：R1代表直链C1到C4烷基，R2代表直链C1到C10烷基，R3代表直链或支链C6到C15烷基，当R1代表正丁基且R2代表乙基时，R3不同于正辛基，正十二烷基，正十八烷基，2-乙基己基和2-乙基辛基。一种合成N，N-二烷基酰胺的方法，以及将其用于从水酸性溶液中提取铀和/或钚，或将铀完全或部分分离出来，其中包含在硝酸中溶解的废旧核燃料的溶液。一种处理由硝酸溶解的废旧核燃料所得的水溶液的方法，该方法允许在单个周期中提取，分离和脱污溶液中含有的铀和钚。
• Stereo‐ and Regiochemical Effect of <i>N,N</i>‐Dialkylamide Extractants on the Speciation of Pu Complexes
  作者：David Lemire、Thomas Dumas、Cécile Marie、Fabrice Giusti、Guilhem Arrachart、Sandrine Dourdain、Stephane Pellet‐Rostaing

  DOI：10.1002/ejic.202300461

  日期：2023.11.14

  The relationship between extractant stereochemistry and their extraction performance has only poorly been established. In order to address a part of this concern, we investigated the Pu(IV) liquid‐liquid extraction (LLE) by using the N,N‐di‐(2‐ethylhexyl)butyramide (DEHBA), as well as those of its position isomers. DEHBA (ββ‐isomer) and N‐(2‐ethylhexyl)‐N‐(oct‐3‐yl)butyramide (EHOBA or αβ‐isomer) were synthesized as a mixture of stereoisomer or stereoenriched (R,S)‐ and (S,S)‐diastereoisomers, and were all assessed for Pu^IV LLE. The results showed that both the position and the stereoisomerism of the aliphatic substituents affect Pu^IV complexation and extraction. We found that Pu extraction is lowered by factor 2 to 4 when the ethyl branching group is closer to the complexing site. UV‐vis spectroscopy showed that this extraction decrease was affected by steric hindrance inducing a deprivation of Pu inner sphere complex. Effect of stereoisomerism is highlighted for branching closer to the complexing site (α‐position). Enantiopure DEHBA stereoisomers provided similar Pu extraction, whereas a slight decrease could be noticed for the more cluttered stereoenriched (αβ)‐isomers, which was also concomitant with a smaller population of inner sphere complex. In contrast, the stereoisomers mixture led to a strong decrease of Pu extraction because of an antagonistic association in the mixed complexes.

  摘要 目前，萃取剂立体化学与萃取性能之间的关系尚不十分明确。为了解决这一问题，我们使用N,N-二（2-乙基己基）丁酰胺（DEHBA）及其位置异构体研究了钚（IV）的液-液萃取（LLE）。DEHBA（ββ-异构体）和N-(2-乙基己基)-N-(辛-3-基)丁酰胺（EHOBA或αβ-异构体）被合成为立体异构体或立体富集的(R,S)-和(S,S)-非对映异构体的混合物，并对它们进行了PuIV LLE评估。结果表明，脂肪族取代基的位置和立体异构体都会影响 PuIV 的络合和萃取。我们发现，当乙基支化基团更靠近络合位点时，钚的萃取率会降低 2 到 4 倍。紫外-可见光谱显示，这种萃取率的降低是受立体阻碍的影响，导致钚内球络合物被剥夺。立体异构的影响突出表现在离络合位点（α 位）较近的分支上。对映体纯 DEHBA 立体异构体的钚萃取率相似，而立体异构体较杂乱的 (αβ) 异构体的钚萃取率略有下降，同时内球复合物的数量也较少。相反，立体异构体混合物由于在混合复合物中存在拮抗作用，导致钚萃取率大大降低。
• Dissymmetric N,N-dialkylamides, the synthesis thereof and uses of same
  申请人：COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

  公开号：US10252983B2

  公开（公告）日：2019-04-09

  Novel dissymmetric N,N-dialkylamides which meet the following formula (I): where R represents a linear or branched alkyl group at C8 to C15. A method for synthesizing these N,N-dialkylamides, and to the uses of same as extractants, alone or in admixture, in order to extract uranium and/or plutonium from an aqueous acid solution, or to totally or separate uranium from plutonium from an aqueous acid solution and, in particular, an aqueous solution resulting from dissolving spent nuclear fuel in nitric acid. Further, a method for processing an aqueous solution resulting from the dissolution of a spent nuclear fuel in nitric acid, allowing the uranium and plutonium contained in the solution to be extracted, separated and decontaminated in a single cycle, without requiring any plutonium reduction operation, and in which one of the aforementioned N,N-dialkylamides or a mixture of same is used as extractant. Applications for the method include the processing of spent nuclear fuels, in particular comprising uranium (e.g. UOX) or uranium and plutonium (e.g. MOX).

  符合下式(I)的新型不对称 N,N-二烷基酰胺： 其中 R 代表 C8 至 C15 的直链或支链烷基。一种合成这些N,N-二烷基酰胺的方法，以及将其作为萃取剂单独或混合使用的方法，以便从酸性水溶液中萃取铀和/或钚，或从酸性水溶液，特别是从将乏核燃料溶解在硝酸中产生的水溶液中完全或分离铀和钚。此外，还有一种用于处理乏核燃料在硝酸中溶解后产生的水溶液的方法，可在一个循环中提取、分离和净化溶液中的铀和钚，而无需进行任何钚还原操作，在该方法中，上述 N,N-二烷基酰胺之一或其混合物被用作提取剂。该方法的应用包括处理乏核燃料，特别是包括铀（如 UOX）或铀和钚（如 MOX）的乏核燃料。
• MUSIKAS, CLAUDE;ZORZ, PHILIPPE
  作者：MUSIKAS, CLAUDE、ZORZ, PHILIPPE

  DOI：——

  日期：——