(3bR,3cR,6aR)-5,5-dimethyl-3-(m-tolyl)-3c,6a,7a,8-tetrahydro-3bH[1,3]dioxolo[4'',5'':4',5']furo[3',2':3,4]pyrrolo[1,2-c][1,2,3]triazol-3b-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (3bR,3cR,6aR)-5,5-dimethyl-3-(m-tolyl)-3c,6a,7a,8-tetrahydro-3bH[1,3]dioxolo[4'',5'':4',5']furo[3',2':3,4]pyrrolo[1,2-c][1,2,3]triazol-3b-ol
• 英文别名: (1R,2R,6R)-4,4-dimethyl-13-(3-methylphenyl)-3,5,7-trioxa-10,11,12-triazatetracyclo[6.6.0.02,6.010,14]tetradeca-11,13-dien-1-ol
• 化学式: C₁₇H₁₉N₃O₄
• 分子量: 329.356
• InChiKey: IHEXCTRSKDNGPJ-OQALIBSHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  78.6
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] SUBSTITUTED SUGAR DERIVED 1, 2, 3-TRIAZOLE COMPOUNDS AND THEIR DIMERS AND A PROCESS FOR THE PREPARATION THEREOF<br/>[FR] COMPOSÉS 1, 2, 3-TRIAZOLES DÉRIVÉS DE SUCRES SUBSTITUÉS ET LEURS DIMÈRES AINSI QU'UN PROCÉDÉ POUR LEUR PRÉPARATION
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2014132273A1

  公开（公告）日：2014-09-04

  The present invention discloses tricyclic five membered sugar derived 1,2,3-triazoles compounds of formula I and their dimers and a process for the preparation thereof. Particularly, the present invention relates to tricyclic five membered sugar derived 1,2,3-triazoles compounds of formula I which are useful for screening of various kinases and other related targets. [Insert formula I here] wherein R is selected from hydrogen, (un)substituted or substituted alkyl, (un)substituted or substituted aryl, (un)substituted or substituted cycloalkyls, (un)substituted or substituted heteroaryls.