Inosine 5'-diphosphate disodium salt | 54735-61-4

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: Inosine 5'-diphosphate disodium salt
• 英文别名: disodium;[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphate
• CAS: 54735-61-4
• 化学式: C10H12N4Na2O11P2
• 分子量: 472.15
• InChiKey: MYSOKTVZCUBKOZ-IDIVVRGQSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -9.29
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  228
• 氢给体数：
  4
• 氢受体数：
  12

安全信息

• 危险性防范说明：
  P280,P305+P351+P338,P310
• 危险性描述：
  H302,H315,H319,H332,H335

制备方法与用途

肌苷-5'-二磷酸二钠盐可用作生化试剂和医药中间体等。

文献信息

• MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF
  申请人：FERRER INTERNACIONAL, S.A.

  公开号：US20220160744A1

  公开（公告）日：2022-05-26

  The present invention relates to a multilayer pharmaceutical or nutraceutical solid dosage form comprising at least one pyrimidine derivative, purine derivative or any salt or solvate thereof and least one B-group vitamin. It also provides three methods for producing said multilayer pharmaceutical or nutraceutical solid dosage forms. Furthermore, the present invention is also related to therapeutic uses of said multilayer pharmaceutical or nutraceutical solid dosage forms, particularly for the treatment and/or prevention of peripheral neuropathy.
• [EN] MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF<br/>[FR] FORMES POSOLOGIQUES SOLIDES PHARMACEUTIQUES OU NUTRACEUTIQUES MULTICOUCHES COMPRENANT DES DÉRIVÉS DE PYRIMIDINE ET/OU DE PURINE ET DES VITAMINES B, LEUR PRÉPARATION ET LEURS UTILISATIONS
  申请人：FERRER INT

  公开号：WO2020224795A1

  公开（公告）日：2020-11-12

  The present invention relates to a multilayer pharmaceutical or nutraceutical solid dosage form comprising at least one pyrimidine derivative, purine derivative or any salt or solvate thereof and least one B-group vitamin. It also provides three methods for producing said multilayer pharmaceutical or nutraceutical solid dosage forms. Furthermore, the present invention is also related to therapeutic uses of said multilayer pharmaceutical or nutraceutical solid dosage forms, particularly for the treatment and/or prevention of peripheral neuropathy.