花生酸异丙酯 | 26718-90-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 花生酸异丙酯
• 英文名称: Arachinsaeure-isopropylester
• 英文别名: isopropyl arachidate；IPA；Isopropyl icosanoate；propan-2-yl icosanoate
• CAS: 26718-90-1
• 化学式: C₂₃H₄₆O₂
• 分子量: 354.617
• InChiKey: WLMTYYBAGSMBPQ-UHFFFAOYSA-N

物化性质

• 熔点：
  53-55 °C
• 沸点：
  394.4±10.0 °C(Predicted)
• 密度：
  0.860±0.06 g/cm3(Predicted)
• LogP：
  10.620 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  10.4
• 重原子数：
  25
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915900090

反应信息

• 作为产物：
  描述：

  二十酸 、 异丙醇 在 对甲苯磺酸 作用下， 反应 72.0h， 以92.3%的产率得到花生酸异丙酯
  参考文献：
  名称：

  Synthesis and Evaluation of Different Fatty Acid Esters Formulated into Precirol ATO-Based Lipid Nanoparticles as Vehicles for Topical Delivery

  摘要：

  合成了一系列不同链长（C13—C23）的异丙基脂肪酸酯，并将其配制成基于Precirol® ATO的脂质纳米颗粒，以评估它们对这些纳米颗粒物理化学特性的影响。此外，还评估了作为脂溶性模型药物的硝酸依康唑的药物负载和皮肤渗透。采用高剪切均质化法制备的纳米系统，平均直径范围为180至280纳米，显示出约100%的包封效率。体外渗透结果表明，脂质纳米颗粒中脂肪酸酯的链长与渗透效果之间呈抛物线相关性。对含有17和19个碳原子的酯的纳米颗粒观察到了最大药物通量，表明这些配方可能成为硝酸依康唑局部给药的潜在载体。

  DOI：

  10.1248/cpb.57.680

文献信息

• Schlenk,W., Justus Liebigs Annalen der Chemie, 1969, vol. 727, p. 1 - 9
  作者：Schlenk,W.

  DOI：——

  日期：——
• PELARGONSÄURE-FORMULIERUNG
  申请人：COMPO GmbH

  公开号：EP2584894B1

  公开（公告）日：2016-06-01
• PELARGONIC ACID FORMULATION
  申请人：Schweinsberg Otto

  公开号：US20130231247A1

  公开（公告）日：2013-09-05

  The present invention relates to a pelargonic acid formulation in the form of an oil-in-water emulsion and the use thereof for controlling undesired vegetation. The herbicidal pelargonic acid formulation according to the invention comprising: a) as component A, pelargonic acid or a mixture of aliphatic C 6 -C 10 -carboxylic acids with a pelargonic acid content of at least 80% by weight based on the total weight of the mixture; b) as component B, at least one organic solvent which under standard conditions has a water solubility of below 1 g/l and which has a boiling point of above 130° C. at standard pressure; c) as component C, at least one surface-active substance which is selected among compounds of the formula I in which n represents 0 or 1, R 1 represents a linear or branched C 6 -C 22 -alkyl radical or a linear or branched C 6 -C 22 -alkenyl radical and R 2 and R 3 independently of one another represent hydrogen or a C 1 -C 4 -alkyl group; d) as component D, at least one nonionic surfactant which is selected among substances which include at least one poly-C 2 -C 4 -oxyalkylene group; e) as component E, at least one amino acid with an isoelectric point in the range of from 5 to 7, and f) water.
• US9743663B2
  申请人：——

  公开号：US9743663B2

  公开（公告）日：2017-08-29
• [EN] PEROXIDE COMPOUNDS FOR THE PREVENTION AND TREATMENT OF SEXUAL DYSFUNCTION IN HUMANS<br/>[FR] COMPOSES DE PEROXYDE POUR LA PREVENTION ET LE TRAITEMENT DE DYSFONCTIONNEMENT SEXUEL CHEZ LES HUMAINS
  申请人：MIDWEST RES LAB LLC

  公开号：WO2005112872A1

  公开（公告）日：2005-12-01

  A composition and method for treatment or prevention of human sexual dysfunction are disclosed. The method contemplates the topical application to a genital organ of composition containing an effective sexual arousal-inducing amount of a peroxide compound. Preferred peroxide compounds include benzoyl peroxide and carbamide peroxide, and mixtures thereof.