Ethane;2-methylpropane;1,2-oxazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: Ethane;2-methylpropane;1,2-oxazole
• 英文别名: ethane;2-methylpropane;1,2-oxazole
• 化学式: C9H19NO
• 分子量: 157.25
• InChiKey: IJUFUJBIMIROPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.36
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Generating cardiac progenitor cells from pluripotent stem cells using isoxazole or isoxazole like compounds
  申请人：Ashraf Muhammad

  公开号：US10443044B2

  公开（公告）日：2019-10-15

  This disclosure provides a chemically modified induced pluripotent stem (iPS) cell derived from parental cells and methods for generating the chemically induced pluripotent stem (iPS) cells, as well as cardiac progenitor cells capable of producing cells of multiple sub-lineages. The iPS cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue or to rejuvenating cardiac muscles in a patient in need thereof and to treat cardiac disease.

  本公开提供了从亲代细胞衍生的化学修饰诱导多能干细胞（iPS）和生成化学诱导多能干细胞（iPS）的方法，以及能够产生多种亚系细胞的心脏祖细胞。iPS 细胞可用于心肌组织的再生，或促进心肌瘢痕组织的替代，或使有需要的患者的心肌恢复活力，以及治疗心脏疾病。
• CPC EXOSOMES MIRNA373 COMBINATION THERAPIES
  申请人：IPS Heart

  公开号：US20210054344A1

  公开（公告）日：2021-02-25

  Steam cell and exosome compositions via combination therapy, related gene therapy and pluripotent stem cell derived muscle regeneration as having therapeutic utility to treat a variety of diseases and disorders, e.g., cardiovascular disease, Duchenne muscular dystrophy, and fibrotic disease.