5-(5-bromo-3,4-dimethylthieno[2,3-b]thiophen-2-yl)-1H-pyrazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩并噻吩类
• 英文名称: 5-(5-bromo-3,4-dimethylthieno[2,3-b]thiophen-2-yl)-1H-pyrazole
• 化学式: C₁₁H₉BrN₂S₂
• 分子量: 313.2
• InChiKey: MUNXAASMRMRSCE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  85.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING BACTERIAL INFECTIONS<br/>[FR] COMPOSÉS, COMPOSITIONS ET MÉTHODES DE TRAITEMENT D'INFECTIONS BACTÉRIENNES
  申请人：DARTMOUTH COLLEGE

  公开号：WO2015094801A1

  公开（公告）日：2015-06-25

  Thieno [2, 3 -b] thiophene compounds and pharmaceutical compositions containing the same are provided for use in inhibiting or suppressing the growth of bacterial pathogens and in the amelioration and treatment bacterial infections, including drug-resistant bacterial infections. Combination therapies including thieno [2, 3 -b] thiophene compounds and beta-lactam antibiotics are also provided.