5-Heptoxyoct-7-enyl acetate | 1253279-23-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-Heptoxyoct-7-enyl acetate
• 英文别名: 5-heptoxyoct-7-enyl acetate
• CAS: 1253279-23-0
• 化学式: C₁₇H₃₂O₃
• 分子量: 284.439
• InChiKey: PEQVBPHVDBFISO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  乙酸酐 、 2-(heptyloxy)tetrahydro-2H-pyran 、 烯丙基三甲基硅烷 在 溴化铋 作用下， 反应 2.58h， 以62%的产率得到5-Heptoxyoct-7-enyl acetate
  参考文献：
  名称：

  Bismuth(III) bromide in organic synthesis. A catalytic method for the allylation of tetrahydrofuranyl and tetrahydropyranyl ethers

  摘要：

  A bismuth bromide-catalyzed (10.0 mol %) multicomponent reaction involving the allylation of THF- and THP-ethers, followed by in situ derivatization with acetic anhydride to generate highly functionalized esters has been developed under solvent-free conditions. To the best of our knowledge, this is the first report of a catalytic procedure for the allylation of THF- and THP-ethers to yield ring-opened products. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.08.079

文献信息

• Bismuth(III) bromide in organic synthesis. A catalytic method for the allylation of tetrahydrofuranyl and tetrahydropyranyl ethers
  作者：Scott W. Krabbe、Veronica V. Angeles、Ram S. Mohan

  DOI：10.1016/j.tetlet.2010.08.079

  日期：2010.10

  A bismuth bromide-catalyzed (10.0 mol %) multicomponent reaction involving the allylation of THF- and THP-ethers, followed by in situ derivatization with acetic anhydride to generate highly functionalized esters has been developed under solvent-free conditions. To the best of our knowledge, this is the first report of a catalytic procedure for the allylation of THF- and THP-ethers to yield ring-opened products. (C) 2010 Elsevier Ltd. All rights reserved.