2-methyl-4,5-bis[(Z)-prop-1-enyl]-1H-imidazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-methyl-4,5-bis[(Z)-prop-1-enyl]-1H-imidazole
• 化学式: C₁₀H₁₄N₂
• 分子量: 162.23
• InChiKey: HNEKTHYRZWGSBB-PEPZGXQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP3239137A1

  公开（公告）日：2017-11-01

  (5R)-4,5-dihydro-isoxazole derivatives as well as 1-(2-chloroacetyl)-4-piperidinecarbonitrile and 1-(2-chloroacetyl)-N-(1,1-dimethylethyl)-4-piperidinecarboxamide as intermediates in the preparation of e.g. 4-[4-[(5R)-4,5-dihydro-isoxazoI-3-yl]-thiazol-2-yl]-piperidine derivatives as fungicides for crop protection. Exemplary intermediates are e.g. N,N-dimethyl-[(5R)-4,5-dihydro-5-phenyl-isoxazol-3-yl]-carboxamide and 2-bromo-[(5R)-4,5-dihydro-5-phenyl-isoxazol-3-yl]-ethanone.

  (5R)-4,5-二氢-异噁唑衍生物以及 1-(2-氯乙酰基)-4-哌啶甲腈和 1-(2-氯乙酰基)-N-(1,1-二甲基乙基)-4-哌啶甲酰胺作为中间体，用于制备例如.g.4-[4-[(5R)-4,5-二氢-异恶唑-I-3-基]-噻唑-2-基]-哌啶衍生物作为作物保护用杀菌剂的中间体。 典型的中间体有 N,N-二甲基-[(5R)-4,5-二氢-5-苯基-异恶唑-3-基]-甲酰胺和 2-溴-[(5R)-4,5-二氢-5-苯基-异恶唑-3-基]-乙酮等。