4-Ethyl-5-(5-brom-2-hydroxy-phenyl)-3-mercapto-4H-1,2,4-triazol | 17076-23-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-Ethyl-5-(5-brom-2-hydroxy-phenyl)-3-mercapto-4H-1,2,4-triazol
• 英文别名: 5-(5-bromo-2-hydroxy-phenyl)-4-ethyl-2,4-dihydro-[1,2,4]triazole-3-thione；4-bromo-2-(4-ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)phenol；3-(5-bromo-2-hydroxyphenyl)-4-ethyl-1H-1,2,4-triazole-5-thione
• CAS: 17076-23-2
• 化学式: C₁₀H₁₀BrN₃OS
• 分子量: 300.179
• InChiKey: IJARAKGQEBNAHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  80
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR
  申请人：RYDER Sean

  公开号：US20110065704A1

  公开（公告）日：2011-03-17

  The invention relates to compositions and methods for inhibiting RNA binding proteins (e.g., MEX-3, MEX-5 and POS-1), as well as methods for treating and preventing disorders associated with parasitic infections and inflammatory disorders.
• US8377639B2
  申请人：——

  公开号：US8377639B2

  公开（公告）日：2013-02-19
• US8962244B2
  申请人：——

  公开号：US8962244B2

  公开（公告）日：2015-02-24
• [EN] COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR<br/>[FR] COMPOSÉS DE MODULATION DES PROTÉINES DE LIAISON À L'ARN ET APPLICATIONS ASSOCIÉES
  申请人：UNIV MASSACHUSETTS

  公开号：WO2010151797A2

  公开（公告）日：2010-12-29

  The invention relates to compositions and methods for inhibiting RNA binding proteins (e.g., MEX-3, MEX-5 and POS-1), as well as methods for treating and preventing disorders associated with parasitic infections and inflammatory disorders.