1-((2Z)-5-{[(1-methylprop-2-en-1-yl)oxy]methyl}hexa-2,5-dien-1-yl)-4-methoxybenzene | 1175163-87-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-((2Z)-5-{[(1-methylprop-2-en-1-yl)oxy]methyl}hexa-2,5-dien-1-yl)-4-methoxybenzene
• 英文别名: 1-[(2Z)-5-(but-3-en-2-yloxymethyl)hexa-2,5-dienyl]-4-methoxybenzene
• CAS: 1175163-87-7
• 化学式: C₁₈H₂₄O₂
• 分子量: 272.387
• InChiKey: PHMSMOSUOJGIKU-SREVYHEPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  p-methoxyphenylbutadiene 、 allyl 1-methylallyl ether 在 CoBr₂(dppe) 、 zinc(II) iodide 、 锌 作用下， 以 二氯甲烷 为溶剂， 以71%的产率得到1-((2Z)-5-{[(1-methylprop-2-en-1-yl)oxy]methyl}hexa-2,5-dien-1-yl)-4-methoxybenzene
  参考文献：
  名称：

  Cobalt-Catalyzed 1,4-Hydrovinylation of Styrenes and 1-Aryl-1,3-butadienes

  摘要：

  The application of aryl-substituted starting materials such as styrene and 1-aryl-substituted 1,3-butadiene derivatives in the cobalt-catalyzed 1,4-hydrovinylation reaction has been investigated. The use of unsymmetrical alpha,omega-dienes in the hydrovinylation with 1-aryl-1,3-butadiene led chemoselectively to the 1:1 or the 1:2 adducts depending on the stoichiometry of the starting materials.

  DOI：

  10.1021/ol901064p

文献信息

• Cobalt-Catalyzed 1,4-Hydrovinylation of Styrenes and 1-Aryl-1,3-butadienes
  作者：Gerhard Hilt、Michael Danz、Jonas Treutwein

  DOI：10.1021/ol901064p

  日期：2009.8.6

  The application of aryl-substituted starting materials such as styrene and 1-aryl-substituted 1,3-butadiene derivatives in the cobalt-catalyzed 1,4-hydrovinylation reaction has been investigated. The use of unsymmetrical alpha,omega-dienes in the hydrovinylation with 1-aryl-1,3-butadiene led chemoselectively to the 1:1 or the 1:2 adducts depending on the stoichiometry of the starting materials.