4-(Triazol-2-yl)butanoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(Triazol-2-yl)butanoic acid
• 英文别名: 4-(triazol-2-yl)butanoic acid
• 化学式: C₆H₉N₃O₂
• 分子量: 155.15
• InChiKey: AWTCJLDVXDJJQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  68
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING TRIAZOLE COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS<br/>[FR] COMPOSITIONS POUR LA TRANSFECTION D'UNE MOLÉCULE D'ACIDE NUCLÉIQUE DANS UNE CELLULE COMPRENANT DES COMPOSÉS DE TRIAZOLE GREFFÉS SUR UN POLYMÈRE CATIONIQUE, ET LEURS APPLICATIONS
  申请人：POLYPLUS TRANSFECTION

  公开号：WO2021023798A1

  公开（公告）日：2021-02-11

  The present invention relates to compositions for transfecting a nucleic acid molecule into a cell and their applications. The present invention is directed to a composition suitable for transfecting a nucleic acid molecule into a cell, preferably a eukaryotic cell, comprising (i) at least one compound of general formula (I), preferably of general formula (III), or a tautomer, mesomer, racemate, enantiomer, diastereomer, or mixture thereof, or an acceptable salt thereof, and (ii) an acceptable excipient, buffering agent, cell culture medium, or transfection medium, wherein Y1, Y2, Y3, Z1, Z2, Z3, X1, X2, R3, P+, R and V are as defined in the description. The present invention also relates to uses of said composition and to a method for in vitro or ex vivo transfection of live cells.