1-allyloxy-3-iodopropan-2-yl acetate | 1421703-55-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-allyloxy-3-iodopropan-2-yl acetate
• 英文别名: (1-Iodo-3-prop-2-enoxypropan-2-yl) acetate；(1-iodo-3-prop-2-enoxypropan-2-yl) acetate
• CAS: 1421703-55-0
• 化学式: C₈H₁₃IO₃
• 分子量: 284.094
• InChiKey: RPQZVLRBYAAFTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  烯丙基缩水甘油醚 、 乙酸酐 在 R₄N⁺I^- (R = n-butyl, n-pentyl, n-hexyl) 作用下， 反应 29.0h， 以74%的产率得到1-allyloxy-3-iodopropan-2-yl acetate
  参考文献：
  名称：

  Catalyst-Free, Direct, High Regio- and Chemoselective Conversion of Epoxides to Vicinal Haloesters Under Mild, Neutral, and Solvent-Free Conditions

  摘要：

  A catalyst-free, high regio- and chemoselective method is described for the mild conversion of wide varieties of epoxides directly to their corresponding vicinal haloesters using quaternary ammonium halides R4N+X- (X equals; Cl, Br, I; R = n-butyl, n-pentyl, n-hexyl) in the presence of an aliphatic or aromatic carboxylic anhydride at room temperature under neutral and solvent-free conditions.

  DOI：

  10.1080/00397911.2011.621097

文献信息

• Catalyst-Free, Direct, High Regio- and Chemoselective Conversion of Epoxides to Vicinal Haloesters Under Mild, Neutral, and Solvent-Free Conditions
  作者：Ghasem Aghapour、Razieh Hatefipour

  DOI：10.1080/00397911.2011.621097

  日期：2013.3.1

  A catalyst-free, high regio- and chemoselective method is described for the mild conversion of wide varieties of epoxides directly to their corresponding vicinal haloesters using quaternary ammonium halides R4N+X- (X equals; Cl, Br, I; R = n-butyl, n-pentyl, n-hexyl) in the presence of an aliphatic or aromatic carboxylic anhydride at room temperature under neutral and solvent-free conditions.