N.N'-Bis-(3-chlor-phenyl)-oxalsaeurediamid | 17738-69-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N.N'-Bis-(3-chlor-phenyl)-oxalsaeurediamid
• 英文别名: N,N'-Di-(3-chlorbenzyl)-oxamid；N,N'-bis-(3-chloro-phenyl)-oxalamide；Oxalsaeure-bis-(3-chlor-anilid)；N,N'-Bis-(3-chlor-phenyl)-oxalamid；N,N'-bis(3-chlorophenyl)oxamide
• CAS: 17738-69-1
• 化学式: C₁₄H₁₀Cl₂N₂O₂
• mdl: MFCD00661245
• 分子量: 309.152
• InChiKey: RXMZIAGDFXNOPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N.N'-Bis-(3-chlor-phenyl)-oxalsaeurediamid 在 五氯化磷 、 甲苯 、 苯 作用下， 生成 2,3-bis-(3-chloro-anilino)-buta-1,3-diene-1,1,4,4-tetracarboxylic acid tetraethyl ester
  参考文献：
  名称：

  SOME DERIVATIVES OF OXANILIDE¹

  摘要：

  DOI：

  10.1021/jo01167a005
• 作为产物：
  描述：

  3-氯苯胺 、 草酸二乙酯 生成 N.N'-Bis-(3-chlor-phenyl)-oxalsaeurediamid
  参考文献：
  名称：

  SOME DERIVATIVES OF OXANILIDE¹

  摘要：

  DOI：

  10.1021/jo01167a005

文献信息

• Heterocycles from heterocycles. 1,3-Diaryl-4,5-imidazolidinediones from 1,3,5-triarylhexahydro-1,3,5-triazines and oxalyl chloride
  作者：Giancarlo Verardo、Angelo G. Giumanini、Fausto Gorassini、Marilena Tolazzi、Paolo Strazzolini

  DOI：10.1016/s0040-4020(01)81552-0

  日期：1993.1

  1,3-Diaryl-4,5-imidazolidinediones ( 6 ) are easily synthesized from 1,3,5-triarylhexahydro-1,3,5-triazines ( 1 ) and oxalyl chloride ( 5 ) in a reaction not likely to involve the zwitterionic intermediate ( 3 ) of the N-methylenearylamine dimer, but viewing the sequential pick up of two units of the monomer ( 2 ) by oxalyl chloride ( 5 ). The essential role of ethyl alcohol added to the reaction mixture is recognized. Reaction conditions have been optimized and some ten imidazolidinediones ( 6 ) were prepared in good to excellent yields. Geometric parameters of 6 were obtained by X-ray diffraction analysis: all the nuclei are found almost in one plane except for a small twist of the phenyl rings about the C-N bond.
• SOME DERIVATIVES OF OXANILIDE¹
  作者：CHARLES C. PRICE、BERNARD H. VELZEN

  DOI：10.1021/jo01167a005

  日期：1947.5