(S)-2-(4-amino-phenyl)-propionic acid amide | 81709-39-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (S)-2-(4-amino-phenyl)-propionic acid amide
• 英文别名: (S)-2-(4-Amino-phenyl)-propionsaeure-amid；(2S)-2-(4-aminophenyl)propanamide
• CAS: 81709-39-9
• 化学式: C₉H₁₂N₂O
• 分子量: 164.207
• InChiKey: YVUJUJYBPUQLQU-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  69.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (S)-4-硝基苯基-2-丙酸 在 甲醇 、 氯化亚砜 、 铂 作用下， 生成 (S)-2-(4-amino-phenyl)-propionic acid amide
  参考文献：
  名称：

  A separation method for DNA computing based on concentration control

  摘要：

  A separation method for DNA computing based on concentration control is presented. The concentration control method was earlier developed and has enabled us to use DNA concentrations as input data and as filters to extract target DNA. We have also applied the method to the shortest path problems, and have shown the potential of concentration control to solve large-scale combinatorial optimization problems. However, it is still quite difficult to separate different DNA with the same length and to quantify individual DNA concentrations. To overcome these difficulties, we use DGGE and CDGE in this paper. We demonstrate that the proposed method enables us to separate different DNA with the same length efficiently, and we actually solve an instance of the shortest path problems.

  DOI：

  10.1007/bf03037359

文献信息

• 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them
  申请人：Dompe' S.P.A.

  公开号：EP2166006A1

  公开（公告）日：2010-03-24

  The present invention relates to (R,S) 2-aryl-propionic acids and derivatives, their single enantiomer (S) and to pharmaceutical compositions containing them, which are used in the prevention and treatment of tissue damage due to the exacerbated recruitment of polymorphonucleated neutrophils (PMN leukocytes) at inflammation sites. The present invention provides compounds for use in the treatment of transient cerebral ischemia, bullous pcmphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and damages caused by ischemia and reperfusion.

  本发明涉及(R,S) 2-芳基丙酸及其衍生物，它们的单对映体(S)，以及含有它们的药物组合物，用于预防和治疗由于在炎症部位过度招募多形核中性粒细胞（PMN白细胞）而导致的组织损伤。 本发明提供了用于治疗短暂性脑缺血、水疱性天疱疮、类风湿关节炎、特发性纤维化、肾小球肾炎以及缺血再灌注引起的损伤的化合物。
• A separation method for DNA computing based on concentration control
  作者：Masahito Yamamoto、Atsushi Kameda、Nobuo Matsuura、Toshikazu Shiba、Yumi Kawazoe、Azuma Ohuchi

  DOI：10.1007/bf03037359

  日期：2002.9

  A separation method for DNA computing based on concentration control is presented. The concentration control method was earlier developed and has enabled us to use DNA concentrations as input data and as filters to extract target DNA. We have also applied the method to the shortest path problems, and have shown the potential of concentration control to solve large-scale combinatorial optimization problems. However, it is still quite difficult to separate different DNA with the same length and to quantify individual DNA concentrations. To overcome these difficulties, we use DGGE and CDGE in this paper. We demonstrate that the proposed method enables us to separate different DNA with the same length efficiently, and we actually solve an instance of the shortest path problems.