trans-3,4-epoxynonane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环氧化物
• 英文名称: trans-3,4-epoxynonane
• 英文别名: trans-3,4-Epoxynonane；(2S,3S)-2-ethyl-3-pentyloxirane
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: BRBFKTQUGYOOEX-IUCAKERBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  反式-3-壬烯 在 二甲基二环氧乙烷 作用下， 以 丙酮 为溶剂， 反应 3.0h， 以99%的产率得到trans-3,4-epoxynonane
  参考文献：
  名称：

  Iodomethane Oxidation by Dimethyldioxirane:  A New Route to Hypoiodous Acid and Iodohydrines

  摘要：

  [GRAPHICS]The oxidation of iodomethane with dimethyldioxirane allows the generation of stable neutral solutions of hypoiodous acid in the absence of any trapping agent for iodide anion. Hypoiodous acid is trapped in situ by addition to representative olefins to give iodohydrines in good yields. The stereochemical study of the products shows the anti-stereospecific nature of the iodohydroxylation reaction.

  DOI：

  10.1021/ol9903281

文献信息

• Iodomethane Oxidation by Dimethyldioxirane:  A New Route to Hypoiodous Acid and Iodohydrines
  作者：Gregorio Asensio、Cecilia Andreu、Carmen Boix-Bernardini、Rossella Mello、María Elena González-Nuñez

  DOI：10.1021/ol9903281

  日期：1999.12.1

  [GRAPHICS]The oxidation of iodomethane with dimethyldioxirane allows the generation of stable neutral solutions of hypoiodous acid in the absence of any trapping agent for iodide anion. Hypoiodous acid is trapped in situ by addition to representative olefins to give iodohydrines in good yields. The stereochemical study of the products shows the anti-stereospecific nature of the iodohydroxylation reaction.