7-咪唑-1-基-庚酸 | 68887-67-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 7-咪唑-1-基-庚酸
• 英文名称: 7-(1-Imidazolyl)heptanoic acid
• 英文别名: 7-imidazol-1-ylheptanoic acid
• CAS: 68887-67-2
• 化学式: C₁₀H₁₆N₂O₂
• mdl: MFCD08668035
• 分子量: 196.25
• InChiKey: KZUXSHYAXPMDNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  55.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Combination of a calcium channel blocker and thromboxane A2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination
  申请人：E.R. SQUIBB & SONS, INC.

  公开号：EP0351755A1

  公开（公告）日：1990-01-24

  A method is provided for treating ischemia in a mammalian species by administering a combination of a calcium channel blocker such as diltiazem, SQ 31,765 or SQ 32,324 and a thromboxane A2 receptor antagonist such as SQ 30,741 or a thromboxane synthetase inhibitor such as dazoxiben.

  本发明提供了一种治疗哺乳动物缺血的方法，即给药钙通道阻滞剂如地尔硫卓、SQ 31,765 或 SQ 32,324 和血栓素 A2 受体拮抗剂如 SQ 30,741 或血栓素合成酶抑制剂如达唑西本的组合。
• Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them
  申请人：BOEHRINGER MANNHEIM ITALIA S.P.A.

  公开号：EP0297621B1

  公开（公告）日：1994-09-21
• METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT
  申请人：Lubit Beverly W.

  公开号：US20110002866A1

  公开（公告）日：2011-01-06

  The described invention relates to delivery of compositions comprising at least one prostaglandin analog to prevent or reduce hair loss (e.g. brittle hair growth, thin hair growth, short hair growth, sparse hair growth) or alopecia associated with chemotherapy.
• METHODS FOR FORMING INCLUSION COMPLEXES WITH HYDROPHILIC BETA-CYCLODEXTRIN DERIVATIVES AND COMPOSITIONS THEREOF
  申请人：TAKA USA, INC.

  公开号：US20200347153A1

  公开（公告）日：2020-11-05

  The described invention provides inclusion complexes of an active agent with a β-cyclodextrin, improved methods for their preparation, methods for characterization of the complexes, and formulation of the complexes as cosmetic compositions or pharmaceutical compositions.
• US4256757A
  申请人：——

  公开号：US4256757A

  公开（公告）日：1981-03-17