hydron;methyl 2,6-diaminohexanoate;dichloride

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: hydron;methyl 2,6-diaminohexanoate;dichloride
• 化学式: C7H18Cl2N2O2
• 分子量: 233.13
• InChiKey: SXZCBVCQHOJXDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.15
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  78.3
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-Thiazolidinecarboxylic acid, 4-(((2,5-dioxo-1-pyrrolidinyl)oxy)carbonyl)-2-phenyl-, 1,1-dimethylethyl ester 、 hydron;methyl 2,6-diaminohexanoate;dichloride 以83%的产率得到
  参考文献：
  名称：

  PAVLOVA L. A.; KOMAROVA T. V.; DAVIDOVICH YU. A.; ROGOZHIN S. V.; PUCHKOV+, XIM.-FARMATS. ZH., 20,(1986) N 9, 1083-1088

  摘要：

  DOI：
• 作为产物：
  描述：

  DL-赖氨酸 、 甲醇 、 氯化亚砜 以76%的产率得到
  参考文献：
  名称：

  SCHUSS. LER, UWE;LEDL, FRANZ, Z. LEBENSM.-UNTERSUCH. UND FORSCH., 189,(1989) N, C. 138-140

  摘要：

  DOI：

文献信息

• INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES
  申请人：Melander Christian

  公开号：US20080181923A1

  公开（公告）日：2008-07-31

  Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.

  提供了关于咪唑衍生物化合物的披露，这些化合物可以预防、去除和/或抑制生物膜的形成，包括这些化合物的组合物、包含这些化合物的设备，以及使用它们的方法。
• INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES
  申请人：Melander Christian

  公开号：US20090143230A1

  公开（公告）日：2009-06-04

  Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.

  本公开提供了一种防止、去除或抑制植物或其部分中微生物生物膜形成或微生物感染的方法，包括向其施加本文所述的活性化合物的有效量或其农业可接受的盐。还提供了增强微生物杀灭剂（例如，包括铜、抗生素、噬菌体等）和/或植物防御激活剂的方法，包括施加本文所述的活性化合物。还提供了包含本文所述的活性化合物在农业可接受载体中的组合物，并在某些实施例中，这些组合物进一步包括微生物杀灭剂（例如，包括铜、抗生素、噬菌体等）和/或植物防御激活剂。
• Diamide compounds and compositions containing the same
  申请人：KOWA CO., LTD.

  公开号：US20010039279A1

  公开（公告）日：2001-11-08

  The present invention relates to compounds represented by the following general formula ( 1 ): 1 wherein A is a phenyl, naphthyl, dihydronaphthyl, indenyl, pyridyl, indolyl, isoindolyl, quinolyl or isoquinolyl group which may be substituted; X is a lower alkylene group which may be substituted, or the like; Y is a single bond or an alkylene group; Z is a group of —CH═CH—, —C≡C—, —(CH═CH) 2 -, —C≡C—CH═CH— or —CH═CH—C≡C—, or the like; and R is a hydrogen atom, a lower alkyl group or the like, and medicines comprising such a compound. These compounds have an excellent inhibitory effect on the production of an IgE antibody and are hence useful as antiallergic agents and the like.

  本发明涉及以下通式（1）所表示的化合物： 其中，A是苯基、萘基、二氢萘基、茚基、吡啶基、吲哚基、异吲哚基、喹啉基或异喹啉基，可以被取代；X是可以被取代的低碳链基或类似物；Y是单键或碳链基；Z是—CH═CH—、—C≡C—、—(CH═CH)2-、—C≡C—CH═CH—或—CH═CH—C≡C—等基团或类似物；R是氢原子、低碳基或类似物，以及包含这种化合物的药物。这些化合物对IgE抗体的产生具有优异的抑制作用，因此可用作抗过敏药物等。
• 2-halomethyl derivatives of 2-amino acids
  申请人：Merrell Dow France et Cie

  公开号：US04743691A1

  公开（公告）日：1988-05-10

  2-(Fluoromethyl or chloromethyl)-2,5-diaminopentanoic acid, 2-(fluoromethyl or chloromethyl)-2,6-diaminohexanoic acid, and 2-fluoromethyl-2-amino-5-guanidinopentanoic acid, and certain derivatives thereof, are inhibitors of ornithine decarboxylase. Methods of preparing the compounds and derivatives are also described.

  2-(氟甲基或氯甲基)-2,5-二氨基戊酸、2-(氟甲基或氯甲基)-2,6-二氨基己酸以及2-氟甲基-2-氨基-5-鸟氨酸基戊酸和其某些衍生物是鸟氨酸脱羧酶的抑制剂。本文还描述了制备这些化合物和衍生物的方法。
• Method for optical resolution of DL-lysine compounds
  申请人：Sumitomo Chemical Company, Limited

  公开号：US04108723A1

  公开（公告）日：1978-08-22

  A method for optical resolution of DL-lysine alkyl ester or acid-addition salts thereof by contacting an aqueous solution of the ester or salts thereof with a non-specific protease obtained by culturing bacteria belonging to the genus Streptomyces, e.g. St. griseus, at weakly acidic pH and a temperature not exceeding 60.degree. C until 60 - 90% by weight of L-lysine ester or acid-addition salts thereof takes part in a reaction, and recovering L-lysine or acid-addition salts thereof thus produced by a conventional manner. The protease may be immobilized on an insoluble carrier in advance.

  一种光学分辨DL-赖氨酸烷基酯或其酸盐的方法，包括将酯或其盐的水溶液与培养属于链霉菌属的细菌（例如灰色链霉菌）所得的非特异性蛋白酶，在微弱酸性pH和不超过60℃的温度下接触，直到L-赖氨酸酯或其酸盐的60-90%参与反应，并通过传统方法回收产生的L-赖氨酸或其酸盐。蛋白酶可以预先固定在不溶性载体上。

表征谱图