N,N'-bis[(2-(2,6-diisopropylphenylamino)benzylidene)]-1,3-propanediamine | 927804-14-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-bis[(2-(2,6-diisopropylphenylamino)benzylidene)]-1,3-propanediamine
• 英文别名: N-[2-[3-[[2-[2,6-di(propan-2-yl)anilino]phenyl]methylideneamino]propyliminomethyl]phenyl]-2,6-di(propan-2-yl)aniline
• CAS: 927804-14-6
• 化学式: C₄₁H₅₂N₄
• 分子量: 600.891
• InChiKey: WZNUMIOPNROCCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.7
• 重原子数：
  45
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  48.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N,N'-bis[(2-(2,6-diisopropylphenylamino)benzylidene)]-1,3-propanediamine 、 diethylzinc 以 甲苯 、 正戊烷 为溶剂， 以57%的产率得到
  参考文献：
  名称：

  由水杨醛亚胺基和苯胺-醛亚胺配体支撑的双金属和聚合锌配位化合物的合成和结构。

  摘要：

  靶向一系列带有水杨基铝亚氨基（1b-3b）或苯胺基-铝二胺（4c-5c）配体骨架的双金属锌络合物，其中金属中心被含有3-6个亚甲基单元的脂族间隔基隔开。具有4个碳间隔基的水杨基铝亚胺衍生物2b的X射线分析显示，固态的配位聚合物，其中每个锌中心被两个水杨基铝亚胺基配体连接。相反，发现具有3个碳亚甲基间隔基的苯胺-醛亚胺络合物4c的结构是离散的双金属络合物。这些差异归因于苯胺给体与苯氧基给体的空间保护不同，后者更容易促进金属中心之间的桥接。

  DOI：

  10.1039/b615080b
• 作为产物：
  描述：

  2,6-二异丙基苯胺 、 N,N'-bis[(2-fluorophenyl)methylene]-1,3-propanediamine 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 24.0h， 以81%的产率得到N,N'-bis[(2-(2,6-diisopropylphenylamino)benzylidene)]-1,3-propanediamine
  参考文献：
  名称：

  Anilido-aldimine aluminum complexes: Synthesis, characterization and lactide polymerization

  摘要：

  The synthesis of six bimetallic dimethyl aluminum anilido-aldimine complexes, active for the ring opening polymerization of rac-lactide, is reported. An efficient synthetic route to these ligands utilizing isolated lithium amide salts allows for the synthesis of novel cyclohexylamide-substituted ligands, as well as improving the yields of diisopropylphenylamino-substituted ligands, with both ethyl and propyl backbones. Less sterically encumbered methylamide-substituted ligands were prepared through the condensation of ortho-methylaminobenzaldehyde with the appropriate diamine. A monometallic intermediate species, L(AlMe2), was isolated and crystallographically characterized, illustrating the preference these ligands display for bis(bidentate) coordination. L(AlMe2)(2) complexes 8-13 are efficient mediators of the ring opening polymerization of rac-lactide, with solution polymerizations displaying first-order rate constants, molecular weights very close to the theoretical values and polydispersity indexes as low as 1.07. (C) 2012 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2012.02.003

文献信息

• Synthesis and structures of bimetallic and polymeric zinc coordination compounds supported by salicylaldiminato and anilido–aldimine ligands
  作者：David J. Doyle、Vernon C. Gibson、Andrew J. P. White

  DOI：10.1039/b615080b

  日期：——

  (1b-3b) or anilido-aldimine (4c-5c) ligand frameworks, in which the metal centres are separated by aliphatic spacer groups containing 3-6 methylene units, were targeted. X-Ray analysis of salicylaldiminato derivative 2b, with a 4 carbon spacer group, revealed a coordination polymer in the solid state where each zinc centre is ligated by two salicylaldiminato ligands. Contrastingly, the structure of the

  靶向一系列带有水杨基铝亚氨基（1b-3b）或苯胺基-铝二胺（4c-5c）配体骨架的双金属锌络合物，其中金属中心被含有3-6个亚甲基单元的脂族间隔基隔开。具有4个碳间隔基的水杨基铝亚胺衍生物2b的X射线分析显示，固态的配位聚合物，其中每个锌中心被两个水杨基铝亚胺基配体连接。相反，发现具有3个碳亚甲基间隔基的苯胺-醛亚胺络合物4c的结构是离散的双金属络合物。这些差异归因于苯胺给体与苯氧基给体的空间保护不同，后者更容易促进金属中心之间的桥接。
• Anilido-aldimine aluminum complexes: Synthesis, characterization and lactide polymerization
  作者：Laura E.N. Allan、Justin A. Bélanger、Laura M. Callaghan、Donald J.A. Cameron、Andreas Decken、Michael P. Shaver

  DOI：10.1016/j.jorganchem.2012.02.003

  日期：2012.6

  The synthesis of six bimetallic dimethyl aluminum anilido-aldimine complexes, active for the ring opening polymerization of rac-lactide, is reported. An efficient synthetic route to these ligands utilizing isolated lithium amide salts allows for the synthesis of novel cyclohexylamide-substituted ligands, as well as improving the yields of diisopropylphenylamino-substituted ligands, with both ethyl and propyl backbones. Less sterically encumbered methylamide-substituted ligands were prepared through the condensation of ortho-methylaminobenzaldehyde with the appropriate diamine. A monometallic intermediate species, L(AlMe2), was isolated and crystallographically characterized, illustrating the preference these ligands display for bis(bidentate) coordination. L(AlMe2)(2) complexes 8-13 are efficient mediators of the ring opening polymerization of rac-lactide, with solution polymerizations displaying first-order rate constants, molecular weights very close to the theoretical values and polydispersity indexes as low as 1.07. (C) 2012 Elsevier B. V. All rights reserved.