dimethyl 5,10-dioxo-6,9-diazatetradecanedioate | 156331-06-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: dimethyl 5,10-dioxo-6,9-diazatetradecanedioate
• 英文别名: Methyl 5-[2-[(5-methoxy-5-oxopentanoyl)amino]ethylamino]-5-oxopentanoate
• CAS: 156331-06-5
• 化学式: C₁₄H₂₄N₂O₆
• 分子量: 316.354
• InChiKey: HXHRKADKFAPKCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  111
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  dimethyl 5,10-dioxo-6,9-diazatetradecanedioate 在 氨 作用下， 以 甲醇 为溶剂， 以75%的产率得到5,10-dioxo-6,9-diazatetradecanediamide
  参考文献：
  名称：

  CHEMOENZYMATIC SYNTHESES OF POLYAMINES AND TETRAAZAMACROCYCLES

  摘要：

  Syntheses of different open chain polyamines starting from enzymatically prepared bis(amidoesters) are described. Some of these polyamines are also used as precursors in the syntheses of tetraazamacrocycles. This methodology cart also be applied to the synthesis of chiral compounds.

  DOI：

  10.1081/scc-120003392
• 作为产物：
  描述：

  戊二酸二甲酯 、 乙二胺 在 Candida antarctica lipase 作用下， 以 1,4-二氧六环 为溶剂， 生成 dimethyl 5,10-dioxo-6,9-diazatetradecanedioate
  参考文献：
  名称：

  CHEMOENZYMATIC SYNTHESES OF POLYAMINES AND TETRAAZAMACROCYCLES

  摘要：

  Syntheses of different open chain polyamines starting from enzymatically prepared bis(amidoesters) are described. Some of these polyamines are also used as precursors in the syntheses of tetraazamacrocycles. This methodology cart also be applied to the synthesis of chiral compounds.

  DOI：

  10.1081/scc-120003392

文献信息

• Astorga, Covadonga; Rebolledo, Francisca; Gotor, Vicente, Journal of the Chemical Society. Perkin transactions I, 1994, # 7, p. 829 - 832
  作者：Astorga, Covadonga、Rebolledo, Francisca、Gotor, Vicente

  DOI：——

  日期：——
• CHEMOENZYMATIC SYNTHESES OF POLYAMINES AND TETRAAZAMACROCYCLES
  作者：Mercedes Rubio、Covadonga Astorga、Ignacio Alfonso、Francisca Rebolledo、Vicente Gotor*

  DOI：10.1081/scc-120003392

  日期：2002.1

  Syntheses of different open chain polyamines starting from enzymatically prepared bis(amidoesters) are described. Some of these polyamines are also used as precursors in the syntheses of tetraazamacrocycles. This methodology cart also be applied to the synthesis of chiral compounds.