7-羟基-5-甲氧基-2-甲基-4-氧代-4H-1-苯并吡喃-6-甲醛 | 7338-51-4

分子结构分类

有机化合物 - 有机杂环化合物 - 苯并吡喃

中文名称

7-羟基-5-甲氧基-2-甲基-4-氧代-4H-1-苯并吡喃-6-甲醛

中文别名

——

英文名称

7-hydroxy-5-methoxy-2-methyl-4-oxo-4H-chromene-6-carbaldehyde

英文别名

6-formyl-7-hydroxy-5-methoxy-2-methylbenzopyran-4-one；7-hydroxy-5-methoxy-4-oxo-4H-chromene-6 carbaldehyde；7-hydroxy-5-methoxy-2-methyl-4-oxochromene-6-carbaldehyde

CAS

7338-51-4

化学式

C₁₂H₁₀O₅

mdl

——

分子量

234.208

InChiKey

HAYPHUYUTZEJQC-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

熔点：

189 °C(Solv: water (7732-18-5))
沸点：

457.6±45.0 °C(Predicted)
密度：

1.384±0.06 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

1.5
重原子数：

17
可旋转键数：

2
环数：

2.0
sp3杂化的碳原子比例：

0.17
拓扑面积：

72.8
氢给体数：

1
氢受体数：

5

SDS

SDS：517683c6e42c19b08a0344e67cd944af

查看

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
齿阿米素	visnagin	82-57-5	C₁₃H₁₀O₄	230.22

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	5,7-dimethoxy-2-methyl-4-oxo-4H-chromene-6-carbaldehyde	91903-64-9	C₁₃H₁₂O₅	248.235
甲基丁香色原酮	5-hydroxy-7-methoxy-2,6-dimethylchromone	480-12-6	C₁₂H₁₂O₄	220.225
——	5,7-dihydroxy-6-formyl-2-methylbenzopyran-4-one	5186-27-6	C₁₁H₈O₅	220.182
——	methyl 7-hydroxy-5-methoxy-2-methylchromone-6-carboxylate	138565-06-7	C₁₃H₁₂O₆	264.235
5,7-二羟基-2,6-二甲基-4H-苯并吡喃-4-酮	5,7-dihydroxy-2,6-dimethylchromone	491-48-5	C₁₁H₁₀O₄	206.198
——	6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]-7-hydroxy-5-methoxy-2-methyl-4H-chromen-4-one	1373132-38-7	C₂₀H₁₆O₅	336.344
——	7-hydroxy-5-methoxy-2-methyl-6-<3-phenyl-3-oxoprop-1-en-1-yl>benzopyran-4(H)-one	108843-96-5	C₂₀H₁₆O₅	336.344
8-溴-7-羟基-5-甲氧基-2-甲基-4-氧代-4H-苯并吡喃-6-甲醛	8-bromo-6-formyl-7-hydroxy-5-methoxy-2-methylbenzopyran-4-one	100124-30-9	C₁₂H₉BrO₅	313.104
——	6-[(1E)-3-(4-bromophenyl)-3-oxoprop-1-en-1-yl]-7-hydroxy-5-methoxy-2-methyl-4H-chromen-4-one	1373132-40-1	C₂₀H₁₅BrO₅	415.24
——	6,7-dihydroxy-5-methoxy-2-methyl-4H-[1]benzopyran-4-one	16623-15-7	C₁₁H₁₀O₅	222.197
——	5-methoxy-8-methyl-2,6-dioxo-2H,6H-benzo<1,2:5,4-b'>dipyran	106038-24-8	C₁₄H₁₀O₅	258.23
——	3-Cyano-2,6-dioxo-5-methoxy-8-methyl-2H,6H-benzo<1,2-b:5,4-b'>dipyran	84734-97-4	C₁₅H₉NO₅	283.24
——	7-hydroxy-6-[3-(6-hydroxy-4,7-dimethoxy-1-benzofuran-5-yl)-3-oxoprop-1-enyl]-5-methoxy-2-methylchromen-4-one	188640-11-1	C₂₄H₂₀O₉	452.417
——	(E)-8-amino-6-(phenyl-3-oxoprop-1-enyl)-7-hydroxy-5-methoxy-2-methyl-4H-chromen-4-one	1373132-45-6	C₂₀H₁₇NO₅	351.359
5,6,7-三羟基-2-甲基-4H-苯并吡喃-4-酮	5,6,7-trihydroxy-2-methylchromone	5186-26-5	C₁₀H₈O₅	208.171
——	(E)-8-amino-6-(4-bromophenyl-3-oxoprop-1-enyl)-7-hydroxy-5-methoxy-2-methyl-4H-chromen-4-one	1373132-47-8	C₂₀H₁₆BrNO₅	430.255
——	(E)-8-amino-6-(3-methoxyphenyl-3-oxoprop-1-enyl)-7-hydroxy-5-methoxy-2-methyl-4H-chromen-4-one	1373132-46-7	C₂₁H₁₉NO₆	381.385
——	5-Methoxy-8-methyl-2,6-dioxo-pyrano[3,2-g]chromene-3-carbothioamide	112434-56-7	C₁₅H₁₁NO₅S	317.322
——	5-Methoxy-8-methyl-2,6-dioxo-pyrano[3,2-g]chromene-3-carbohydrazide	112434-54-5	C₁₅H₁₂N₂O₆	316.27
——	2-imino-5-methoxy-8-methyl-6-oxo-3-thiocarboxamide-2H,6H-benzo<1,2-b:5,4-b'>dipyran	112434-57-8	C₁₅H₁₂N₂O₄S	316.337
——	3-benzoyl-2-imino-5-methoxy-8-methyl-2H,6H-pyrano[3,2-g]chromen-6-one	112434-58-9	C₂₁H₁₅NO₅	361.354
——	3-carbohydrazide-2-imino-5-methoxy-8-methyl-6-oxo-2H,6H-benzo<1,2-b:5,4-b'>dipyran	112434-55-6	C₁₅H₁₃N₃O₅	315.285
——	7-hydroxy-5-methoxy-2-methyl-6-(4-phenyl-2-sulfanylidene-5,6-dihydro-1H-pyrimidin-6-yl)chromen-4-one	1373132-48-9	C₂₁H₁₈N₂O₄S	394.451
——	6-(benzimidazol-2-yl)-7-hydroxy-5-methoxy-2-methylchromone	212193-39-0	C₁₈H₁₄N₂O₄	322.32
——	2-[Amino-(5-methoxy-8-methyl-2,6-dioxo-pyrano[3,2-g]chromen-3-yl)methylene]propanedinitrile	112434-59-0	C₁₈H₁₁N₃O₅	349.302
——	6-[4-(4-bromophenyl)-2-sulfanylidene-5,6-dihydro-1H-pyrimidin-6-yl]-7-hydroxy-5-methoxy-2-methylchromen-4-one	1373132-50-3	C₂₁H₁₇BrN₂O₄S	473.347
——	2-[Amino-(2-imino-5-methoxy-8-methyl-6-oxo-pyrano[3,2-g]chromen-3-yl)methylene]propanedinitrile	112434-64-7	C₁₈H₁₂N₄O₄	348.318
——	8-bromo-7-hydroxy-5-methoxy-2-methyl-4-thioxo-4H-benzopyran-6-carbaldehyde	1239279-31-2	C₁₂H₉BrO₄S	329.171
——	7-hydroxy-5-methoxy-6-[4-(3-methoxyphenyl)-2-sulfanylidene-5,6-dihydro-1H-pyrimidin-6-yl]-2-methylchromen-4-one	1373132-49-0	C₂₂H₂₀N₂O₅S	424.477
——	3-(4-Fluorophenyl)-2-imino-5-methoxy-8-methylpyrano[3,2-g]chromen-6-one	1100363-95-8	C₂₀H₁₄FNO₄	351.334
——	3-(4-Chlorophenyl)-2-imino-5-methoxy-8-methylpyrano[3,2-g]chromen-6-one	1100363-96-9	C₂₀H₁₄ClNO₄	367.788
——	2-Imino-5-methoxy-8-methyl-3-(4-nitrophenyl)pyrano[3,2-g]chromen-6-one	1100363-97-0	C₂₀H₁₄N₂O₆	378.341
——	4-[2-(4-Aminophenyl)-2-oxo-ethyl]-2-imino-5-methoxy-8-methyl-6-oxo-3,4-dihydropyrano[3,2-g]chromene-3-carboxamide	174088-07-4	C₂₃H₂₁N₃O₆	435.436
——	3-(2,4-Dichlorophenyl)-2-imino-5-methoxy-8-methylpyrano[3,2-g]chromen-6-one	1100363-98-1	C₂₀H₁₃Cl₂NO₄	402.234
——	3-[amino-(3,5-diaminopyrazol-4-ylidene)methyl]-5-methoxy-8-methylpyrano[3,2-g]chromene-2,6-dione	112434-62-5	C₁₈H₁₅N₅O₅	381.348
——	4-[2-(4-Amino-phenyl)-2-oxo-ethyl]-2-imino-5-methoxy-8-methyl-6-oxo-3,4-dihydro-2H,6H-pyrano[3,2-g]chromene-3-carboxylic acid hydrazide	174088-08-5	C₂₃H₂₂N₄O₆	450.451
——	3-[amino-(3,5-diaminopyrazol-4-ylidene)methyl]-2-imino-5-methoxy-8-methylpyrano[3,2-g]chromen-6-one	112434-63-6	C₁₈H₁₆N₆O₄	380.363
——	5-methoxy-8-methyl-2,6-dioxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]pyrano[3,2-g]chromene-3-carboxamide	1402580-85-1	C₂₄H₁₇N₃O₈S₂	539.546
——	2-imino-5-methoxy-8-methyl-6-oxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]pyrano[3,2-g]chromene-3-carboxamide	1402580-84-0	C₂₄H₁₈N₄O₇S₂	538.562

反应信息

作为反应物：

描述：

7-羟基-5-甲氧基-2-甲基-4-氧代-4H-1-苯并吡喃-6-甲醛在二氧化锰、溶剂黄146 作用下，以甲醇、水、乙酸乙酯为溶剂，以80%的产率得到methyl 7-hydroxy-5-methoxy-2-methylchromone-6-carboxylate

参考文献：

名称：

Heterocyclic compounds: 2-styryl-4H-1-benzopyran-4-ones

摘要：

式(I)的化合物##STR1##其中：R.sub.1代表氢原子、较低的烷基基团、羟基或较低的烷氧基团，R.sub.2、R.sub.3、R.sub.4、R.sub.5、R.sub.6、R.sub.7、R.sub.8和R.sub.11如描述中所定义。药物。

公开号：