2-Bicyclo[2.2.1]hept-5-en-2-yl-propionaldehyde | 142405-69-4

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氧化物
• 英文名称: 2-Bicyclo[2.2.1]hept-5-en-2-yl-propionaldehyde
• 英文别名: 2-{Bicyclo[2.2.1]hept-5-en-2-yl}propanal；2-(2-bicyclo[2.2.1]hept-5-enyl)propanal
• CAS: 142405-69-4
• 化学式: C₁₀H₁₄O
• 分子量: 150.221
• InChiKey: HOOOMCWTAWHKCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  三甲基氯硅烷 、 (endo-methyl-2 bicyclo<2.2.1>heptene-5) yl-2 ethyl cetone 、 2-Bicyclo[2.2.1]hept-5-en-2-yl-propionaldehyde 生成 (4S,5R,6S)-6-Bicyclo[2.2.1]hept-5-en-2-yl-2,4-dimethyl-5-trimethylsilanyloxy-hept-1-en-3-one 、 (4R,5S,6S)-6-Bicyclo[2.2.1]hept-5-en-2-yl-2,4-dimethyl-5-trimethylsilanyloxy-hept-1-en-3-one
  参考文献：
  名称：

  Endo-2-methyl-bicyclo[2.2.1]-hept-5enyl ethyl ketone: an useful and highly stereoselective synthon for aldol reactions

  摘要：

  An excellent aldehyde diastereofacial selectivity has been observed during the aldol condensation between the lithium enolate of endo-2-methyl-bicyclo[2.2.1]-hept-5-enyl ethyl ketone 1 and a variety of alpha-methyl chiral aldehydes. 2-Aryl- and 2-vinyl-propionaldehyde gave rise to the predicted syn, syn "Felkin-Anh" diastereoisomers. In contrast beta-alkoxy or beta-silyloxy alpha-methyl aldehydes lead to the syn, anti aldols arising from an apparent chelation control.

  DOI：

  10.1016/s0040-4039(00)92225-1

文献信息

• Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof
  申请人：Imuta Junichi

  公开号：US20090137757A1

  公开（公告）日：2009-05-28

  A polar group-containing olefin copolymer having excellent adhesion properties to metals or polar resins and excellent compatibility therewith, a process for preparing the copolymer, a thermoplastic resin composition containing the copolymer, and uses thereof. The polar group-containing olefin copolymer comprises a constituent unit derived from an □-olefin of 2 to 20 carbon atoms, and a constituent unit derived from a straight-chain, branched or cyclic polar group-containing monomer having at the end a polar group such as a hydroxyl group or an epoxy group and/or a constituent unit derived from a macromonomer having at the end a polymer segment obtained by anionic polymerization, ring-opening polymerization or polycondensation. The polar group-containing olefin copolymer can be prepared by polymerizing the α-olefin with the polar group-containing monomer and/or the macromonomer in the presence of a metallocene catalyst. The polar group-containing olefin copolymer and the thermoplastic resin composition containing the copolymer are used for films, sheets, modifiers, building/civil engineering materials, automobile exterior trim, electric/electronic parts, coating bases, compatibilizing agents, etc.
• US7714087B2
  申请人：——

  公开号：US7714087B2

  公开（公告）日：2010-05-11
• Endo-2-methyl-bicyclo[2.2.1]-hept-5enyl ethyl ketone: an useful and highly stereoselective synthon for aldol reactions
  作者：Mohammed Ahmar、Robert Bloch、Gérard Mandville、Isabelle Romain

  DOI：10.1016/s0040-4039(00)92225-1

  日期：1992.4

  An excellent aldehyde diastereofacial selectivity has been observed during the aldol condensation between the lithium enolate of endo-2-methyl-bicyclo[2.2.1]-hept-5-enyl ethyl ketone 1 and a variety of alpha-methyl chiral aldehydes. 2-Aryl- and 2-vinyl-propionaldehyde gave rise to the predicted syn, syn "Felkin-Anh" diastereoisomers. In contrast beta-alkoxy or beta-silyloxy alpha-methyl aldehydes lead to the syn, anti aldols arising from an apparent chelation control.