N-(2,4-difluorophenyl)carbamodithioate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,4-difluorophenyl)carbamodithioate
• 化学式: C₇H₄F₂NS₂
• 分子量: 204.244
• InChiKey: RQTATDBHQQPAPI-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  45.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-(2,4-difluorophenyl)carbamodithioate 在 三光气 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成 2,4-二氟异硫氰酸苯酯
  参考文献：
  名称：

  Synthesis and nematicidal activity of piperazinedione derivatives based on the natural product Barettin

  摘要：

  Nematodes are serious constraints of crop production worldwide. However, the traditional nematicides suffer from the side-effects, including environmental and human toxicity. Herein, more than 70 novel piperazinedione derivatives based on the natural product Barettin were synthesized and evaluated against the root-knot nematode Meloidogyne incognita (M. incognita). While most of synthesized compounds exhibited certain nematicidal activity at high concentration, the best one showed a nematicidal activity of 75% at 2.4 mu mol/L. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cclet.2017.10.015
• 作为产物：
  描述：

  二硫化碳 、 2,4-二氟苯胺 在 三乙烯二胺 作用下， 以 四氢呋喃 为溶剂， 反应 24.0h， 生成 N-(2,4-difluorophenyl)carbamodithioate
  参考文献：
  名称：

  Synthesis and nematicidal activity of piperazinedione derivatives based on the natural product Barettin

  摘要：

  Nematodes are serious constraints of crop production worldwide. However, the traditional nematicides suffer from the side-effects, including environmental and human toxicity. Herein, more than 70 novel piperazinedione derivatives based on the natural product Barettin were synthesized and evaluated against the root-knot nematode Meloidogyne incognita (M. incognita). While most of synthesized compounds exhibited certain nematicidal activity at high concentration, the best one showed a nematicidal activity of 75% at 2.4 mu mol/L. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cclet.2017.10.015