Luteoliflavan | 446-06-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: Luteoliflavan
• 英文别名: (2S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-5,7-diol
• CAS: 446-06-0
• 化学式: C₁₅H₁₄O₅
• 分子量: 274.27
• InChiKey: GWCPBEMISACTHQ-AWEZNQCLSA-N

物化性质

• 沸点：
  570.4±50.0 °C(Predicted)
• 密度：
  1.480±0.06 g/cm3(Predicted)
• 熔点：
  185 °C(Solv: water (7732-18-5))

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  90.2
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• LITCHI PRODUCTS AS DERMATOLOGICAL AND COSMETIC AGENTS
  申请人：Dr. August Wolff GmbH & Co. KG Arzneimittel

  公开号：EP3862050A1

  公开（公告）日：2021-08-11

  The present invention relates to a litchi product and use thereof as a skin or hair care product, in particular as a cosmetic or as a (dermatological) pharmaceutical agent. The litchi product of the invention is suitable for and effective in restoring the physiological pH of skin or hair and/or in protecting the skin or hair against oxidative stress e.g. caused by light irradiation and other environmental influences. It is effective in the medical and cosmetic treatment and prophylaxis of several skin or hair diseases and conditions. Moreover, the invention relates to a process for preparing the litchi product.

  本发明涉及一种荔枝产品及其作为皮肤或头发护理产品的用途，特别是作为化妆品或 （皮肤病）药物制剂的用途。本发明的荔枝产品适用于恢复皮肤或头发的生理 pH 值和/或保护皮肤或头发免受氧化压力（如光照射和其他环境影响引起的氧化压力），并具有这种效果。它对多种皮肤或头发疾病和病症的医疗和美容治疗及预防有效。此外，本发明还涉及荔枝产品的制备工艺。
• APPROACH FOR SYNTHESIS OF CATECHINS
  申请人：Epirium Bio Inc.

  公开号：EP2948437B1

  公开（公告）日：2021-11-03
• XANTHONE-RICH PLANT EXTRACTS OR COMPOUNDS THEREFROM FOR MODULATING DISEASES OF THE CENTRAL NERVOUS SYSTEM AND RELATED DISORDERS
  申请人：DEAKIN UNIVERSITY

  公开号：EP3110414B1

  公开（公告）日：2020-09-30
• Phenolic Coatings and Methods of Making and Using Same
  申请人：Messersmith Phillip B.

  公开号：US20140206630A1

  公开（公告）日：2014-07-24

  A method of making a facile, surface-independent, polyphenol coating is disclosed. In general, the method includes contacting at least a portion of the substrate to be coated with an aqueous solution containing one or more salts and one or more nitrogen-free phenolic compounds. Substrates of all kinds may be used, and compounds used to make the coating may include epigallocatechin-3-gallate (EGCG), epigallocatechin (EGC) and epicatechin-3-gallate (ECG), tannic acid, gallic acid, pyrogallol, and/or other nitrogen-free phenolic compounds. The coating made using the method, methods of using the coating, and kits comprising the coating precursors are also disclosed.
• [EN] THERMALLY-PROCESSED COCOA PRODUCTS USEFUL FOR VASCULAR HEALTH IMPROVEMENT<br/>[FR] PRODUITS A BASE DE CACAO THERMIQUEMENT TRAITES UTILISES DANS L'AMELIORATION DE LA SANTE VASCULAIRE
  申请人：MARS INC

  公开号：WO2007002851A2

  公开（公告）日：2007-01-04

  [EN] The invention relates to compositions containing polyphenols such as flavanols, procyanidins, and derivatives thereof obtainable by thermally treating the polyphenols in an aqueous solution, and to compositions comprising epimers of flavanols, procyanidins, and derivatives thereof, and methods of therapeutic or prophylactic treatment of NO-responsive diseases or disorders using the same. The invention also relates to thermally-processed cocoa powders and cocoa extracts characterized by an altered monomelic and oligomeric profile where the total amount of epicatechin and catechin is unchanged, where new dimers are present, and where oligomers higher than the trimers are absent.
  [FR] L'invention concerne des compositions qui contiennent des polyphénols tels que les flavanols, les procyanidines, et des dérivés de ceux-ci obtenus par traitement thermique des polyphénols dans une solution aqueuse; des compositions qui contiennent des épimères de flavanols, de procyanidines, et des dérivés de ceux-ci; ainsi que des méthodes thérapeutiques ou prophylactiques des maladies ou de troubles réceptifs au monoxyde d'azote, qui font intervenir ces compositions. Par ailleurs, l'invention concerne des poudres et des extraits de cacao thermiquement traités caractérisés par un profil monomélique et oligomérique modifié, dans lesquelles la quantité totale de l'épicatéchine et de la catéchine reste inchangé, de nouveaux dimères sont présents, et des oligomères plus élevés que les trimères sont absents.

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