18-(2-Thienyl)octadecanoic Acid | 26359-19-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 18-(2-Thienyl)octadecanoic Acid
• 英文别名: 18-Thiophen-2-yloctadecanoic acid
• CAS: 26359-19-3
• 化学式: C₂₂H₃₈O₂S
• 分子量: 366.609
• InChiKey: VCORQLYXZFXVOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  25
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  65.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  18-(2-Thienyl)octadecanoic Acid 在 磷酸 、 三氟乙酸酐 作用下， 以 乙腈 为溶剂， 以98%的产率得到23-Thia-bicyclo[18.2.1]tricosa-1(22),20-dien-2-one
  参考文献：
  名称：

  Ring-closure reactions. 14. Kinetics of macrocyclization by the intramolecular acylation of thiophene and benzothiophene compounds

  摘要：

  DOI：

  10.1021/jo01290a022
• 作为产物：
  描述：

  十八二酸单甲酯 在 hydroxide 、 肼 作用下， 生成 18-(2-Thienyl)octadecanoic Acid
  参考文献：
  名称：

  Ring-closure reactions. 16. An improved procedure for the synthesis of (2,5)thiophenophan-1-ones and its application to a convenient preparation of dl-muscone

  摘要：

  DOI：

  10.1021/jo01298a029

文献信息

• Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds
  申请人：Upshaw Thomas A.

  公开号：US20090264669A1

  公开（公告）日：2009-10-22

  The application discloses thiol ester molecules and α-hydroxy thiol ester molecules having a thiol group located on one of the final two carbon atoms in a carbon chain or a terminal or α-hydroxyl groups, respectively. The disclosed thiol ester molecules and or α-hydroxyl thiol ester molecules es may be made from unsaturated ester molecules having one or more terminal alkene groups. The disclosed techniques also provide methods for making unsaturated ester molecules having one or more terminal alkene groups by the metathesis of unsaturated esters having one or more internal carbon-carbon double bonds (e.g. natural source oils). The thiol ester molecules or α-hydroxy thiol ester molecule may be used in reactions with isocyanate monomers, epoxide monomer, or material having multiple alkene groups to make sealants, coatings, adhesives, and other products.

  本发明揭示了具有巴豆醇基位于碳链的最后两个碳原子之一或具有末端或α-羟基的巴豆醇酯分子和α-羟基巴豆醇酯分子。所述的巴豆醇酯分子或α-羟基巴豆醇酯分子可以由具有一个或多个末端烯烃基团的不饱和酯分子制备而成。本发明还提供了通过不饱和酯类之间的交换反应（例如天然源油）制备具有一个或多个末端烯烃基团的不饱和酯分子的方法。巴豆醇酯分子或α-羟基巴豆醇酯分子可以与异氰酸酯单体，环氧单体或具有多个烯烃基团的材料反应，制备密封剂，涂料，粘合剂和其他产品。
• CATONI G.; GALLI C.; MANDOLINI L., J. ORG. CHEM., 1980, 45, NO 10, 1906-1908
  作者：CATONI G.、 GALLI C.、 MANDOLINI L.

  DOI：——

  日期：——
• US8765984B2
  申请人：——

  公开号：US8765984B2

  公开（公告）日：2014-07-01
• [EN] METHODS AND SYSTEMS FOR MAKING THIOL COMPOUNDS FROM TERMINAL OLEFINIC COMPOUNDS<br/>[FR] PROCÉDÉS ET SYSTÈMES DE FABRICATION DE COMPOSÉS THIOL À PARTIR DE COMPOSÉS OLÉFINIQUES TERMINAUX
  申请人：CHEVRON PHILLIPS CHEMICAL CO

  公开号：WO2009132010A1

  公开（公告）日：2009-10-29

  The application discloses thiol ester molecules and α-hydroxy thiol ester molecules having a thiol group located on one of the final two carbon atoms in a carbon chain or a terminal or α- hydroxyl groups, respectively. The disclosed thiol ester molecules and or α- hydroxyl thiol ester molecules es may be made from unsaturated ester molecules having one or more terminal alkene groups. The disclosed techniques also provide methods for making unsaturated ester molecules having one or more terminal alkene groups by the metathesis of unsaturated esters having one or more internal carbon-carbon double bonds (e.g. natural source oils). The thiol ester molecules or α-hydroxy thiol ester molecule may be used in reactions with isocyanate monomers, epoxide monomer, or material having multiple alkene groups to make sealants, coatings, adhesives, and other products.
• Ring-closure reactions. 16. An improved procedure for the synthesis of (2,5)thiophenophan-1-ones and its application to a convenient preparation of dl-muscone
  作者：Giuseppe Catoni、Carlo Galli、Luigi Mandolini

  DOI：10.1021/jo01298a029

  日期：1980.5