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6-Methyl-1H-imidazo[1,2-b]pyrazole

中文名称
——
中文别名
——
英文名称
6-Methyl-1H-imidazo[1,2-b]pyrazole
英文别名
6-methyl-5H-imidazo[1,2-b]pyrazole
6-Methyl-1H-imidazo[1,2-b]pyrazole化学式
CAS
——
化学式
C6H7N3
mdl
——
分子量
121.14
InChiKey
FQBWCTIOVJKGIP-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    1.1
  • 重原子数:
    9
  • 可旋转键数:
    0
  • 环数:
    2.0
  • sp3杂化的碳原子比例:
    0.17
  • 拓扑面积:
    33.1
  • 氢给体数:
    1
  • 氢受体数:
    1

反应信息

  • 作为产物:
    描述:
    2-(2,2-diethoxy-ethyl)-5-methyl-2H-pyrazol-3-ylamine 、 、 硫酸disodium;carbonate乙醇 为溶剂, 反应 5.0h, 以to provide 1.4 g of 6-methylimidazo[1,2-b]pyrazole的产率得到6-Methyl-1H-imidazo[1,2-b]pyrazole
    参考文献:
    名称:
    Method for forming magenta color image
    摘要:
    使用含有芳香基一级胺的显影液,在以下一般式(I)所代表的偶联剂存在下,研制了一种银卤感光材料:##STR1## 其中,R1、R2和R3分别表示氢原子或某种取代基团,X表示氢原子或偶联可消除基团,以提供具有高色纯度的品红色图像。
    公开号:
    US04500630A1
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文献信息

  • Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses
    申请人:L'OREAL
    公开号:US20040231067A1
    公开(公告)日:2004-11-25
    The subject of the present application is a dyeing composition for dyeing keratinous fibres, in particular human keratinous fibres such as hair, comprising, in an appropriate dyeing medium, at least one cationic tertiary para-phenylenediamine containing a pyrrolidine ring, and at least one particular heterocyclic coupler. The subject of the invention is also the dyeing method using this composition.
    本申请的主题是一种染色组合物,用于染色角蛋白纤维,特别是人类角蛋白纤维,如头发,包括在适当的染料介质中,至少包含一种含有吡咯烷环的阳离子第三对苯二胺,以及至少一种特定的杂环偶合剂。本发明的主题还包括使用该组合物的染色方法。
  • Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent
    申请人:——
    公开号:US20040237220A1
    公开(公告)日:2004-12-02
    The invention relates to a dye composition comprising an oxidation base of the diaminopyrazole type and a pyrazolo-azole coupler. The invention also relates to the use of this composition for dyeing keratin fibres and also to the dyeing process using this composition.
    本发明涉及一种染料组合物,包括二氨基吡唑基氧化物基和吡唑啉-唑类偶合剂。本发明还涉及使用该组合物染色角蛋白纤维的方法,以及使用该组合物进行染色过程的方法。
  • Novel azole derivatives
    申请人:Otake Norikazu
    公开号:US20080188507A1
    公开(公告)日:2008-08-07
    The present invention relates to a compound of the formula (I): wherein Az is a group comprising a monocyclic azole or a bicyclic aromatic ring of the same or different fused azoles; T, U, V and W are independently methine or nitrogen, said methine being optionally substituted by a substituent, and at least two of T, U, V and W are said methine groups; and X is nitrogen or methine. The compounds of the present invention are useful as agents for the treatment of various kinds of diseases related to NPY, for example, cardiovascular disorders, nervous system disorders, genitative diseases, metabolic diseases, genital or reproductive disorders, gastro-intestinal disorders, respiratory disorders, inflammatory diseases or glaucoma, and the like.
    本发明涉及式(I)的化合物,其中Az是包括单环唑或相同或不同的融合唑的双环芳香环的基团;T、U、V和W独立地为亚甲或氮,所述亚甲可以被取代,且至少有两个T、U、V和W是所述亚甲基团;X为氮或亚甲。本发明的化合物可用作治疗与NPY相关的各种疾病的药剂,例如心血管疾病、神经系统疾病、遗传疾病、代谢性疾病、生殖器或生殖系统疾病、胃肠疾病、呼吸系统疾病、炎症性疾病或青光眼等。
  • Method of producing magenta images in silver halide colour photographic materials
    申请人:FUJI PHOTO FILM CO., LTD.
    公开号:EP0119741A2
    公开(公告)日:1984-09-26
    A silver halide photosensitive material is developed with a developing solution containing an aromatic amine in the presence of a coupler of the general formula: wherein R1, R2 and R3 each represents a hydrogen atom or a substituent group, and X represents a hydrogen atom or a coupling eliminable group; 46 specific couplers are shown, and four synthesis methods. An aromatic color stabilizer may be present. Magenta color image of high color purity is formed.
    用含有芳香胺的显影液在通式如下的耦合剂存在下对卤化感光材料进行显影: 其中 R1、R2 和 R3 各代表一个氢原子或一个取代基团,X 代表一个氢原子或一个可消除偶联的基团;共显示了 46 种特定的偶联剂和四种合成方法。可能存在芳香族颜色稳定剂。形成高色纯度的品红色图像。
  • New cephem compounds and processes for preparation thereof
    申请人:FUJISAWA PHARMACEUTICAL CO., LTD.
    公开号:EP0427248A2
    公开(公告)日:1991-05-15
    A compound of the formula wherein R1 is amino or a protected amino group, R2 is hydrogen or an organic group, R3 is hydrogen, lower alkyl, hydrory(lower)alkyl, protected hydroxy(lower)alkyl, amino(lower)alkyl, protected amino(lower)alkyl, carbamoyl-(lower)alkyl, N,N-di(lower)alkylcarbamoyl(lower)alkyl or an imino protective group, R4 is hydrogen, lower alkyl, carboxy, protected carboxy, amino,protected amino or carbamoyl, and Z is N or CH, and a pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient in admixture with pharmaceutically acceptable carriers. The invention also relates to intermediates of the formula and processes for their preparation.
    式中的化合物 其中 R1 是基或受保护的基、 R2 是氢或有机基团 R3 是氢、低级烷基 R3是氢、低级烷基、羟基(低级)烷基、受保护的羟基(低级)烷基、基(低级)烷基、受保护的基(低级)烷基、基甲酰基(低级)烷基、N,N-二(低级)烷基基甲酰基(低级)烷基或亚胺保护基团、 R4 是氢、低级烷基、羧基、保护羧基、基、保护基或基甲酰基,以及 Z 是 N 或 CH、 及其药学上可接受的盐、 它们的制备工艺,以及将它们作为活性成分与药学上可接受的载体混合的药物组合物。本发明还涉及式 及其制备工艺。
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