2-mercapto-tetradecanoic acid | 126660-84-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-mercapto-tetradecanoic acid
• 英文别名: 2-Mercapto-tetradecansaeure；2-Mercapto-myristinsaeure；α-Mercapto-myristinsaeure；2-Mercaptotetradecanoic acid；2-sulfanyltetradecanoic acid
• CAS: 126660-84-2
• 化学式: C₁₄H₂₈O₂S
• 分子量: 260.441
• InChiKey: ITOLXGQFDAFXMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  38.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-mercapto-tetradecanoic acid 在 乙醇 、 碘 作用下， 生成 2,5-didodecyl-3,4-dithia-adipic acid
  参考文献：
  名称：

  Eggerth, Journal of Experimental Medicine, 1931, vol. 53, p. 28

  摘要：

  DOI：
• 作为产物：
  描述：

  2-溴十四酸 在 sodium hydrogensulfide 、 乙醇 作用下， 生成 2-mercapto-tetradecanoic acid
  参考文献：
  名称：

  Eggerth, Journal of Experimental Medicine, 1931, vol. 53, p. 28

  摘要：

  DOI：

文献信息

• Pharmacy students' perceptions of their profession relative to other health care professions
  作者：Vicky Kritikos、Erica J Sainsbury、Sinthia Z Bosnic-Anticevich、Helen M G Watt

  DOI：10.1211/0022357021242

  日期：2010.2.18

  (1) To investigate pharmacy students' perceptions of 10 occupations within the medical and allied professions: community pharmacists, dentists, dietitians, general medical practitioners (GPs), hospital pharmacists, medical specialists, nurses, occupational therapists, physiotherapists and social workers. (2) To explore students' perceptions of community and hospital pharmacists at different stages of a four-year undergraduate programme and at the year of pre-registration training.

  A 90-item questionnaire was administered to 543 pharmacy undergraduates and 95 graduates undergoing their pre-registration year training in 2001.

  Faculty of Pharmacy, The University of Sydney, Australia.

  Students perceived the health care professions along three major dimensions, relating to “empathy”, “potency” and “expertise”. On an empathy dimension, students rated community pharmacists the highest and medical specialists the lowest. On a potency dimension, students rated medical specialists the most powerful, community and hospital pharmacists significantly lower, and nurses the lowest. On an expertise dimension, students rated medical specialists the highest and dietitians the lowest. A significant pattern of differences was noted in students' perceptions and a possible decline was identified in the potency rating of pharmacists at different stages of the pharmacy programme.

  These differences may be attributed to the differences in the students' value systems, skills and experiences, the influence of reference groups and the content and structure of the educational and training programme in each year.

  (1) 调查药学生对医疗和相关职业中的10种职业的认知：社区药剂师、牙医、营养师、全科医生、医院药剂师、医学专家、护士、职业治疗师、物理治疗师和社工。(2) 探讨学生对四年本科课程和预注册培训年的社区和医院药剂师的认知。

  在2001年，向543名药学本科生和95名正在进行预注册年培训的毕业生进行了90项问卷调查。

  澳大利亚悉尼大学药学院。

  学生认为医疗保健职业有三个主要维度，与“同理心”、“效能”和“专业知识”有关。在同理心维度上，学生评价社区药剂师最高，医学专家最低。在效能维度上，学生认为医学专家最强大，社区和医院药剂师显著较低，护士最低。在专业知识维度上，学生认为医学专家最高，营养师最低。发现了学生认知上的差异，并在药学课程的不同阶段中发现了药剂师效能评价的可能下降趋势。

  这些差异可能归因于学生价值观、技能和经验的差异，参考群体的影响以及每年教育和培训计划的内容和结构。

• LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS
  申请人：OOHASHI Hidekazu

  公开号：US20110054212A1

  公开（公告）日：2011-03-03

  A lithographic printing plate precursor, which comprises: a support; an image-recording layer; and a protective layer, in this order, wherein at least one of the image-recording layer and the protective layer comprises a phosphonium salt having a specific structure, and a lithographic printing process, which comprises: exposing a lithographic printing plate precursor; supplying an oil-based ink and a fountain solution comprising a phosphonium salt having a specific structure to the exposed lithographic printing plate precursor on a printing machine to remove an unexposed area of an image-recording layer; and conducting printing.

  一种光刻印刷版前体，包括：支撑体；图像记录层；以及保护层，依次排列，其中图像记录层和保护层中至少有一层包含具有特定结构的磷酸铵盐；以及一种光刻印刷工艺，包括：曝光光刻印刷版前体；在印刷机上向曝光的光刻印刷版前体提供具有特定结构的磷酸铵盐的油墨和喷泉溶液，以去除图像记录层中未曝光区域；进行印刷。
• Thickener for aqueous systems
  申请人：ROHM AND HAAS COMPANY

  公开号：EP1120451A1

  公开（公告）日：2001-08-01

  Aqueous compositions having enhanced thickening properties containing lipophilically modified copolymer thickeners and one or more hydrophilic surfactants are disclosed. In particular, aqueous compositions containing (i) lipophilically modified copolymers containing at least 5% of selected lipophilically modified components and (ii) surfactants having an HLB value of greater than 15 are useful for the thickening of a range of personal, domestic and industrial products.

  本发明公开了具有增强增稠特性的水性组合物，其中包含亲油改性共聚物增稠剂和一种或多种亲水性表面活性剂。特别是含有以下成分的水性组合物：(i) 亲油改性共聚物，其中至少含有 5%的选定亲油改性成分；(ii) HLB 值大于 15 的表面活性剂，可用于一系列个人、家用和工业产品的增稠。
• Nonionic oligomeric surfactants and their use as dispersants and stabilisers
  申请人：EASTMAN KODAK COMPANY

  公开号：EP1122279A2

  公开（公告）日：2001-08-08

  A hydrophobically capped oligomeric acrylamide or pyrrolidone is employed as a dispersant for hydrophobic materials in an aqueous medium containing a hydrophilic colloid, e.g. gelatin. The hydrophobic materials include photographic addenda such as colour couplers or solid particle dyes. Preferred dispersants have the general formula         R-L-T     (1) or    in which R, R1 and R2 are each independently selected from aliphatic hydrocarbyl, aryl(aliphatic hydrocarbyl) and (aliphatic hydrocarbyl)-aryl groups, L is a sulphur atom or a linking group that contains a sulphur atom attached to the T group, and T is a hydrophilic oligomeric group obtained by the oligomerisation of one or more vinyl monomers having an amido function.

  在含有亲水胶体（如明胶）的水介质中，使用疏水封端的低聚丙烯酰胺或吡咯烷酮作为疏水材料的分散剂。疏水性材料包括照相添加剂，如颜色耦合剂或固体颗粒染料。首选的分散剂通式为 R-L-T (1) 或 其中 R、R1 和 R2 各自独立地选自脂族烃基、芳基（脂族烃基）和（脂族烃基）-芳基、 L 是硫原子或含有硫原子的连接基团，连接到 T 基团上，以及 T 是亲水低聚物基团，由一种或多种具有氨基功能的乙烯基单体低聚而得。
• Thickener for high-surfactant aqueous systems
  申请人：ROHM AND HAAS COMPANY

  公开号：EP1402877A1

  公开（公告）日：2004-03-31

  An aqueous composition comprising at least 18% surfactant and colloidal inorganic clay, This composition is stable with regard to phase separation at 40°C for at least three months and exhibits increased low-shear viscosity relative to a composition without clay. The composition comprises at least one lipophilically-modified copolymer containing acrylic acid residues and C2-C4 alkyl (meth)acrylate residues.

  由至少 18% 的表面活性剂和胶体无机粘土组成的水性组合物，该组合物在 40°C 温度下至少三个月内相分离稳定，与不含粘土的组合物相比，低剪切粘度增加。该组合物包含至少一种亲脂改性共聚物，其中含有丙烯酸残基和 C2-C4 烷基（甲基）丙烯酸酯残基。