methyl [3,3'-di-t-butyl-5,5'-dimethoxy-1,1'-biphenyl-2,2'-diyl] phosphite | 103815-79-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: methyl [3,3'-di-t-butyl-5,5'-dimethoxy-1,1'-biphenyl-2,2'-diyl] phosphite
• 英文别名: 4,8-Ditert-butyl-2,6,10-trimethoxybenzo[d][1,3,2]benzodioxaphosphepine
• CAS: 103815-79-8
• 化学式: C₂₃H₃₁O₅P
• 分子量: 418.47
• InChiKey: OFZZGXODNUXMCS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  反-2-丁烯 、 methyl [3,3'-di-t-butyl-5,5'-dimethoxy-1,1'-biphenyl-2,2'-diyl] phosphite 生成 异戊醛
  参考文献：
  名称：

  BILLIG, ERNST;ABATJOGLOU, ANTHONY G.;BRYANT, DAVID R.;MURRAY, REX E.;MAHE+

  摘要：

  DOI：
• 作为产物：
  描述：

  甲醇 、 (S)-1,1'-binaphthyl-2,2'-diyl methyl phosphite 在 氮甲基苯胺三氟乙酸 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 生成 methyl [3,3'-di-t-butyl-5,5'-dimethoxy-1,1'-biphenyl-2,2'-diyl] phosphite
  参考文献：
  名称：

  Solid-Phase Parallel Synthesis of Phosphite Ligands

  摘要：

  Various routes for the synthesis of polymer-bound phosphites and phosphoramidites have been investigated. In the presence of a suitable activator the supported phosphoramidites react cleanly with alcohols to give the corresponding monodentate phosphite ligands in solution. We have applied this novel solid-phase route in the parallel synthesis of several monodentate chiral and achiral phosphite ligands.

  DOI：

  10.1021/ol703070x

文献信息

• Process for producing aldehyde acids or salts thereof
  申请人：UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION

  公开号：EP0872469A1

  公开（公告）日：1998-10-21

  This invention relates in part to processes for producing one or more substituted or unsubstituted aldehyde acids or salts, e.g., 5-formylvaleric acid or salt, which comprises subjecting one or more substituted or unsubstituted alkadienes, e.g., butadiene, to hydroxycarbonylation in the presence of a hydroxycarbonylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, and optionally neutralization with a base to produce one or more substituted or unsubstituted unsaturated acids or salts, e.g., pentenoic acid or salt, and subjecting said one or more substituted or unsubstituted unsaturated acids or salts to hydroformylation in the presence of a hydroformylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, to produce said one or more substituted or unsubstituted aldehyde acids or salts and/or one or more substituted or unsubstituted epsilon caprolactam precursors. This invention also relates in part to reaction mixtures containing one or more substituted or unsubstituted aldehyde acids or salts as the principal product(s) of reaction.

  本发明部分涉及生产一种或多种取代或未取代的醛酸或盐，例如 5-甲酰基戊酸或盐的工艺，其中包括将一种或多种取代或未取代的烯烃，例如丁二烯，在羟基羰基化催化剂，例如金属有机磷配位体络合物催化剂存在下进行羟基羰基化，并可选择地用碱中和、丁二烯，在羟基羰基化催化剂（如金属有机磷配位体络合物催化剂）存在下进行羟基羰基化，并可选择用碱中和，以生成一种或多种取代或未取代的不饱和酸或盐，如戊烯酸或盐，并使所述一种或多种取代或未取代的不饱和酸或盐在氢甲酰化催化剂（如金属有机磷配位体络合物催化剂）存在下进行氢甲酰化反应，以生成所述一种或多种取代或未取代的醛酸或盐和/或一种或多种取代或未取代的epsilon己内酰胺前体。本发明还部分涉及含有一种或多种取代或未取代醛酸或盐作为主要反应产物的反应混合物。
• Process for producing epsilon caprolactones from penten-1-ols
  申请人：UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION

  公开号：EP0872483A1

  公开（公告）日：1998-10-21

  This invention relates in part to processes for producing one or more substituted or unsubstituted epsilon caprolactones and/or hydrates and/or esters thereof which comprise subjecting one or more substituted or unsubstituted penten-1-ols to carbonylation in the presence of a carbonylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, to produce said one or more substituted or unsubstituted epsilon caprolactones and/or hydrates and/or esters thereof. The substituted and unsubstituted epsilon caprolactones and/or hydrates and/or esters thereof produced by the processes of this invention can undergo further reaction(s) to afford desired derivatives thereof, e.g., epsilon caprolactam. This invention also relates in part to reaction mixtures containing one or more substituted or unsubstituted epsilon caprolactones and/or hydrates and/or esters thereof as principal product(s) of reaction.

  本发明部分涉及生产一种或多种取代或未取代的epsilon己内酯和/或其水合物和/或酯的工艺，该工艺包括在羰基化催化剂（如金属-有机磷配位体络合物催化剂）存在下，将一种或多种取代或未取代的戊烯-1-醇进行羰基化，以生产所述一种或多种取代或未取代的epsilon己内酯和/或其水合物和/或酯。通过本发明工艺生产的取代和未取代的epsilon己内酯和/或其水合物和/或酯类可通过进一步反应得到所需的衍生物，如epsilon己内酰胺。本发明还部分涉及含有一种或多种取代或未取代的epsilon己内酯和/或其水合物和/或酯作为主要反应产物的反应混合物。
• Improved metal-ligand complex catalyzed processes
  申请人：UNION CARBIDE CHEMICALS & PLASTICS

  公开号：EP1108707A1

  公开（公告）日：2001-06-20

  This invention relates to a person for separating one or more phosphorus acidic compounds from a reaction product fluid containing said one or more phosphorus acidic compounds, a metal-organophosphite ligand complex catalyst and optionally free organophosphite ligand which process comprises (a) treating said reaction product fluid with water sufficient to remove at least some amount of said one or more phosphorus acidic compounds from said reaction product fluid and (b) treating the water which contains phosphorus acidic compounds removed from said reaction product fluid with an acid removal substance sufficient to remove at least some amount of said one or more phosphorus acidic compounds from said water.

  本发明涉及一种从含有一种或多种磷酸性化合物的反应产物流体中分离一种或多种磷酸性化合物的方法、本发明涉及一种从含有一种或多种磷酸性化合物的反应产物流体中分离出一种或多种磷酸性化合物的工艺，该工艺包括：(a) 用足以从反应产物流体中去除至少一定量的所述一种或多种磷酸性化合物的水处理所述反应产物流体；(b) 用足以从所述水中去除至少一定量的所述一种或多种磷酸性化合物的脱酸物质处理从所述反应产物流体中去除的含有磷酸性化合物的水。
• Hydroformylation process
  申请人：Dow Technology Investments LLC

  公开号：US10023516B2

  公开（公告）日：2018-07-17

  Catalytic metal loss when using a hydroformylation catalyst comprising an organophosphite ligand is ameliorated by adding CO to a strip gas vaporizer.

  通过在带状气体蒸发器中加入一氧化碳，可改善使用包含有机膦配体的加氢甲酰化催化剂时的催化金属损失。
• Processes for producing organophosphorous compounds
  申请人：Dow Technology Investments LLC

  公开号：US10239901B2

  公开（公告）日：2019-03-26

  The present invention relates to processes for producing organophosporous compositions having low acid content as well as processes for reprocessing partially degraded organophosporous compositions that contain high levels of phosphorous acid. In one embodiment, a process comprises: (a) receiving a solid organophosphite compound that has been recrystallized or triturated, wherein the solid organophosphite compound comprises phosphorous acid; (b) dissolving the solid organophosphite compound in an organic solvent; (c) treating the solution with a weakly basic adsorbent; and (d) collecting the treated organophosphite solution, wherein the acid content of the organophosphite following step (d) is 30 ppm or less.

  本发明涉及酸含量低的有机多孔化合物的生产工艺，以及部分降解的含磷酸含量高的有机多孔化合物的再加工工艺。在一个实施方案中，工艺包括：(a)接收重结晶或三凝固的固体有机亚磷酸酯化合物，其中固体有机亚磷酸酯化合物包含磷酸；(b)将固体有机亚磷酸酯化合物溶解在有机溶剂中；(c)用弱碱性吸附剂处理溶液；以及(d)收集处理后的有机亚磷酸酯溶液，其中步骤(d)后的有机亚磷酸酯的酸含量为 30 ppm 或更低。