Ph2P(O)NH(C6H3iPr2-2,6) | 1224839-46-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Ph2P(O)NH(C6H3iPr2-2,6)
• 英文别名: N-diphenylphosphoryl-2,6-di(propan-2-yl)aniline
• CAS: 1224839-46-6
• 化学式: C₂₄H₂₈NOP
• 分子量: 377.466
• InChiKey: GRCCZYJRVXTABI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Ph2P(O)NH(C6H3iPr2-2,6) 、 甲基磺酰氯 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 4.0h， 以38%的产率得到(OPPh2)(O2SMe)N(C6H3iPr2-2,6)
  参考文献：
  名称：

  New Organophosphorus Proligands and Amide Precursors: Crystal and Molecular Structures of Ph₂P(X)NH(C₆H₃Prⁱ ₂-2,6) (X = O, S) and (OPPh₂)(O₂SMe)N(C₆H₃Prⁱ ₂-2,6)

  摘要：

  The new organophosphorus proligand (OPPh2)(O2SMe)NR (R = C6H3Pri2-2,6) (3) was prepared as a white crystalline solid by reacting the lithiated compound Li[Ph2P(O)NR] with MeSO2Cl in a 1:1 molar ratio. The precursor Ph2P(O)NHR (1), as well as its thio analogue Ph2P(S)NHR (2), were obtained in the reaction between the lithiated amine RNHLi and the corresponding organophosphorus chloride. All compounds were characterized by multinuclear (1H, 13C, and 31P) NMR spectroscopy. The molecular structures of 1-3 were established by single-crystal X-ray diffraction. A zigzag polymeric chain is formed in the crystals of 1 and 2 by hydrogen N-H center dot center dot center dot X (X = O, S) bonding, while the crystal of 3 contains discrete monomeric units with a syn-syn conformation of the O=P(C)2-N-S(C)(=O)2 skeleton. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

  DOI：

  10.1080/10426500903029464
• 作为产物：
  描述：

  N-(2,6-diisopropylphenyl)-1,1-diphenylphosphanamine 在 双氧水 作用下， 以 水 为溶剂， 生成 Ph2P(O)NH(C6H3iPr2-2,6)
  参考文献：
  名称：

  合成和新（N-二苯基膦基）表征-isopropylanilines和它们的复合物：（Ph2PS）NH的晶体结构？C6H4 ？4 ？CH（CH3）2和钯（II）配合物在Heck和Suzuki交叉偶联反应中的催化活性

  摘要：

  由氯二苯基膦与2-异丙基苯胺，4-异丙基苯胺或4-甲基苯胺的氨解反应制得了三个在碳2-（1）4-（2）或2,6-（3）上具有异丙基取代基的新的（N-二苯基膦基）异丙基苯胺2,6-二异丙基苯胺分别在厌氧条件下使用。的1,2-氧化和3与过氧化氢水溶液，元素硫或硒灰色得到相应的氧化物，硫化物和硒化物（PH 2 PE）NH  Ç 6 ħ 4  2-CH（CH 3）2，（PH 2 PE）NH  ç 6 ħ 4  4-CH（CH 3）2和（PH 2 PE）NH  Ç 6 ħ 4  2,6- {CH（CH 3）2 } 2，E = O，S，或Se，其中分别。[M（COD）Cl组成的反应2与1,2-二当量或3倍的产率相应的monodendate络合物[M（（PH;]（COD = 1,5-环辛二烯M =钯，铂）2 P）NH  ç 6 ħ 4  2-CH（CH 3）2）2氯2 ]，M =钯1d中，M

  DOI：

  10.1002/aoc.1576

文献信息

• Synthesis of Nonsymmetric Iminophosphonamines by Kirsanov Condensation
  作者：Tatyana A. Peganova、Alexander M. Kalsin

  DOI：10.1055/s-0039-1690242

  日期：2020.2

  Despite the growing interest in iminophosphonamines R2P(NHR′)(NR′), nonsymmetric examples bearing different N,N′-substituents are quite rare and have been prepared exclusively by the Staudinger reaction. We report here the synthesis of a series of new iminophosphonamines Ph2P(NHR)(NR′) (R = Me, t-Bu, o-Tol; R′ = p-Tol, o-Tol, 2,6-Xyl, 2,6-Diip, p-Ts) showing that the Kirsanov condensation is a viable

  尽管对亚氨基膦胺R 2 P（NHR'）（NR'）的兴趣日益增长，但带有不同N，N'-取代基的非对称实例非常少见，并且仅通过Staudinger反应制备。我们在这里报告了一系列新的亚氨基膦胺Ph 2 P（NHR）（NR'）的合成（R = Me，t -Bu，o -Tol; R'= p -Tol，o -Tol，2,6-Xyl ，2,6-Diip，p-Ts）表明，尽管有一些限制，但Kirsanov缩合是一种可行且更简单的方法。该方法允许通过三卤代磷烷的逐步双胺化以一锅法完成合成，并允许引入至少一种空间上庞大的N-取代基。已显示出第二个胺化步骤对以下物质高度敏感：（a）胺的空间体积，和（b）氨基卤代intermediate中间体的酸度。
• Phosphoramidate catalysts for ethylene-based interpolymers
  申请人：Dow Global Technologies LLC

  公开号：US11168155B2

  公开（公告）日：2021-11-09

  Catalyst systems contain metal-ligand complexes according to formula (I): In formula (I), M is Ti, Zr, of Hf; n is 0, 1, 2, or 3; m is 1 or 2; each R1 and each R2 is independently chosen from (C1-C40)hydrocarbyl, (C1-C40)heterohydrocarbyl, (C1-C40)aryl, (C1-C40)heteroaryl, halogen, and —H; R1 and R2 are optionally covalently linked to each other; and each R3 is a hydrocarbon or heterohydrocarbon radical having an identity depending on the value of subscript m. The metal-ligand complexes may be incorporated as procatalysts in catalyst systems for polyolefin polymerization.

  催化剂体系包含符合式（I）的金属配体复合物：在式 (I) 中，M 是 Ti、Zr 或 Hf；n 是 0、1、2 或 3；m 是 1 或 2；每个 R1 和每个 R2 独立地选自 (C1-C40)烃基、(C1-C40)杂烃基、(C1-C40)芳基、(C1-C40)杂芳基、卤素和-H；R1 和 R2 任选地彼此共价连接；每个 R3 是烃基或杂烃基，其特性取决于下标 m 的值。金属配体复合物可作为催化剂加入聚烯烃聚合的催化剂体系中。
• [EN] PHOSPHORAMIDATE CATALYSTS FOR ETHYLENE-BASED INTERPOLYMERS<br/>[FR] CATALYSEURS AU PHOSPHORAMIDATE DESTINÉS À DES INTERPOLYMÈRES À BASE D'ÉTHYLÈNE
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2018160610A1

  公开（公告）日：2018-09-07

  Catalyst systems contain metal-ligand complexes according to formula (I): In formula (I), M is Ti, Zr, of Hf; n is 0, 1, 2, or 3; m is 1 or 2; each R1 and each R2 is independently chosen from (C1-C40)hydrocarbyl, (C1-C40)heterohydrocarbyl, (C1-C40)aryl, (C1-C40)heteroaryl, halogen, and -H; R1 and R2 are optionally covalently linked to each other; and each R3 is a hydrocarbon or heterohydrocarbon radical having an identity depending on the value of subscript m. The metal-ligand complexes may be incorporated as procatalysts in catalyst systems for polyolefin polymerization.
• Synthesis and characterization of new (<i>N</i>-diphenylphosphino)-isopropylanilines and their complexes: crystal structure of (Ph₂P<b></b>S)NHC₆H₄4CH(CH₃)₂and catalytic activity of palladium(II) complexes in the Heck and Suzuki cross-coupling reactions
  作者：Murat Aydemir、Akın Baysal、Nevin Gürbüz、İsmail Özdemir、Bahattin Gümgüm、Saim Özkar、Nagihan Çaylak、Leyla Tatar Yıldırım

  DOI：10.1002/aoc.1576

  日期：——

  selenides (Ph2PE)NHC6H42‐CH(CH3)2, (Ph2PE)NHC6H44‐CH(CH3)2 and (Ph2PE)NHC6H42,6‐CH(CH3)2}2, where E = O, S, or Se, respectively. The reaction of [M(cod)Cl2] (M = Pd, Pt; cod = 1,5‐cyclooctadiene) with two equivalents of 1,2 or 3 yields the corresponding monodendate complexes [M((Ph2P)NHC6H42‐CH(CH3)2)2Cl2], M = Pd 1d, M = Pt 1e, [M((Ph2P)NHC6H44‐CH(CH3)2)2Cl2], M = Pd 2d, M = Pt 2e and [M((Ph2P)NHC6H42

  由氯二苯基膦与2-异丙基苯胺，4-异丙基苯胺或4-甲基苯胺的氨解反应制得了三个在碳2-（1）4-（2）或2,6-（3）上具有异丙基取代基的新的（N-二苯基膦基）异丙基苯胺2,6-二异丙基苯胺分别在厌氧条件下使用。的1,2-氧化和3与过氧化氢水溶液，元素硫或硒灰色得到相应的氧化物，硫化物和硒化物（PH 2 PE）NH  Ç 6 ħ 4  2-CH（CH 3）2，（PH 2 PE）NH  ç 6 ħ 4  4-CH（CH 3）2和（PH 2 PE）NH  Ç 6 ħ 4  2,6- CH（CH 3）2 } 2，E = O，S，或Se，其中分别。[M（COD）Cl组成的反应2与1,2-二当量或3倍的产率相应的monodendate络合物[M（（PH;]（COD = 1,5-环辛二烯M =钯，铂）2 P）NH  ç 6 ħ 4  2-CH（CH 3）2）2氯2 ]，M =钯1d中，M
• New Organophosphorus Proligands and Amide Precursors: Crystal and Molecular Structures of Ph₂P(X)NH(C₆H₃Prⁱ ₂-2,6) (X = O, S) and (OPPh₂)(O₂SMe)N(C₆H₃Prⁱ ₂-2,6)
  作者：Alpar Pöllnitz、Sevil Irisli、Cristian Silvestru、Anca Silvestru

  DOI：10.1080/10426500903029464

  日期：2010.3.24

  The new organophosphorus proligand (OPPh2)(O2SMe)NR (R = C6H3Pri2-2,6) (3) was prepared as a white crystalline solid by reacting the lithiated compound Li[Ph2P(O)NR] with MeSO2Cl in a 1:1 molar ratio. The precursor Ph2P(O)NHR (1), as well as its thio analogue Ph2P(S)NHR (2), were obtained in the reaction between the lithiated amine RNHLi and the corresponding organophosphorus chloride. All compounds were characterized by multinuclear (1H, 13C, and 31P) NMR spectroscopy. The molecular structures of 1-3 were established by single-crystal X-ray diffraction. A zigzag polymeric chain is formed in the crystals of 1 and 2 by hydrogen N-H center dot center dot center dot X (X = O, S) bonding, while the crystal of 3 contains discrete monomeric units with a syn-syn conformation of the O=P(C)2-N-S(C)(=O)2 skeleton. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.