BW723C86盐酸盐 | 160521-72-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: BW723C86盐酸盐
• 中文别名: BW 723C86盐酸盐
• 英文名称: BW 723C86 hydrochloride
• 英文别名: 1-[5-(thiophen-2-ylmethoxy)-1H-indol-3-yl]propan-2-amine;hydrochloride
• CAS: 160521-72-2
• 化学式: C16H19ClN2OS
• 分子量: 322.9
• InChiKey: PYJBJMIBANAOFJ-UHFFFAOYSA-N

物化性质

• 溶解度：
  二甲基亚砜：>10 mg/mL

计算性质

• 辛醇/水分配系数(LogP)：
  4.12
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  79.3
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• WGK Germany：
  3
• RTECS号：
  NL8504715
• 海关编码：
  2934999090

文献信息

• Serotonergic compositions and methods for treatment of mild cognitive impairment
  申请人：——

  公开号：US20020173511A1

  公开（公告）日：2002-11-21

  A method of treating Mild Cognitive Impairment has been discovered. The treatment method comprises administering an effective amount of a serotonergic agent, including, but not limited to dexnorfenfluramine. The agent can be any serotonergic agonist, partial agonist, serotonin reuptake inhibitor, or combinations of these agents. The treatment method also encompasses combinations of serotonergic agents and non-steroidal anti-inflammatory agents. The treatment method may also delay the onset of Mild Cognitive Impairment, dementia, or both.

  现已发现一种治疗轻度认知障碍的方法。该治疗方法包括施用有效量的血清素能制剂，包括但不限于右诺芬氟拉明。该药物可以是任何血清素能激动剂、部分激动剂、血清素再摄取抑制剂或这些药物的组合。治疗方法还包括血清素能药物和非甾体抗炎药物的组合。治疗方法还可以延缓轻度认知功能障碍、痴呆或两者的发生。
• [EN] MEDICAMENTS FOR TREATMENT OF MIGRAINE, EPILEPSY AND FEEDING DISORDERS<br/>[FR] MEDICAMENTS POUR LE TRAITEMENT DE LA MIGRAINE, DE L'EPILEPSIE ET DES TROUBLES DE L'ALIMENTATION
  申请人：——

  公开号：WO1994025012A2

  公开（公告）日：1994-11-10

  [EN] A novel method of medical treatment, in particular the treatment and prevention of epilepsy and migraine.
  [FR] L'invention concerne une nouvelle méthode de traitement médical et plus particulièrement le traitement et la prévention de l'épilepsie et de la migraine.
• [EN] SEROTONERGIC COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT<br/>[FR] COMPOSITIONS SEROTONINERGIQUES ET METHODES DE TRAITEMENT DE LA DEFICIENCE COGNITIVE LEGERE
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2002038142A2

  公开（公告）日：2002-05-16

  A method of treating Mild Cognitive Impairment has been discovered. The treatment method comprises administering an effective amount of a serotonergic agent, including, but not limited to dexnorfenfluramine. The agent can be any serotonergic agonist, partial agonist, serotonin reuptake inhibitor, or combinations of these agents. The treatment method also encompasses combinations of serotonergic agents and non-steroidal anti-inflammatory agents. The treatment method may also delay the onset of Mild Cognitive Impairment, dementia, or both.