2-ethyl-5-propyl-furan | 158394-76-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-ethyl-5-propyl-furan
• 英文别名: 2-Aethyl-5-propyl-furan；2-Ethyl-5-propylfuran
• CAS: 158394-76-4
• 化学式: C₉H₁₄O
• 分子量: 138.21
• InChiKey: SBTMCCFONKAYRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-ethyl-5-propyl-furan 在 盐酸 、 硫化氢 作用下， 以 乙醇 为溶剂， 生成 2-ethyl-5-propylthiophene
  参考文献：
  名称：

  Investigation of the mechanism of the recyclization of furans to thiophenes and selenophenes under acid-catalysis conditions. 3. Investigation of the recyclization of homologs and functional derivatives of furan. Quantum-chemical calculations of the objects of the recyclization

  摘要：

  DOI：

  10.1007/bf00531398
• 作为产物：
  描述：

  2-乙基呋喃 在 氢氧化钾 、 四氯化锡 、 一水合肼 、 二乙二醇 作用下， 生成 2-ethyl-5-propyl-furan
  参考文献：
  名称：

  Fetizon; Baranger, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1953, vol. 236, p. 499

  摘要：

  DOI：

文献信息

• Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
  申请人：Castro C. Alfredo

  公开号：US20070155705A1

  公开（公告）日：2007-07-05

  The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

  本发明涉及结合到Bcl蛋白并抑制Bcl功能的杂环化合物，包括这些化合物的组合物，以及用于治疗和调节与高增殖相关的疾病，如癌症的方法。
• Isoprenyl Compounds and Methods Thereof
  申请人：Stock Jeffry B.

  公开号：US20100184768A1

  公开（公告）日：2010-07-22

  Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical, cosmetic, cosmeceutical and topical compositions comprising these isoprenyl compounds. Anti-inflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with inflammation. Proinflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with suppression of inflammatory responses. Thus, the present invention also provides methods useful in the treatment or prevention of diseases or conditions associated with inflammation as well as methods useful in the treatment or prevention of diseases or conditions associated with suppression of inflammatory responses.

  除其他事项外，本发明提供了新型异戊二烯基化合物，能够有效调节炎症反应，并提供包含这些异戊二烯基化合物的药物、化妆品、化妆品和局部组合物。本发明的抗炎化合物可用于治疗或预防与炎症相关的疾病或症状。本发明的促炎化合物可用于治疗或预防与抑制炎症反应相关的疾病或症状。因此，本发明还提供了用于治疗或预防与炎症相关的疾病或症状以及用于治疗或预防与抑制炎症反应相关的疾病或症状的方法。
• DIRECT SYNTHESIS OF BIO-BASED ALKYL & FURANIC DIOL ETHERS, ACETATES, ETHER-ACETATES, AND CARBONATES
  申请人：ARCHER DANIELS MIDLAND COMPANY

  公开号：US20170001971A1

  公开（公告）日：2017-01-05

  A method of preparing a glycol mono-ether or mono-acetate, or carbonate involving either one of two pathways from alkylene glycols, HMF or its reduction derivative products (i.e., FDM, bHMTHFs), is provided. In particular, according to one pathway, the alkylene glycol, HMF or FDM, bHMTHFs are reacted with a dialkyl carbonate in the presence of a deprotonating agent, in substantial absence of an extrinsic catalyst, to produce an ether, and subsequently reacting the ether with an acid base. According to the other pathway, alkylene glycols are reacted with an acetate donor in the presence of an acid, base, to generate an alkylene monoacetate, and etherified with a carbonate in the presence of a deprotonating agent.
• US7745464B2
  申请人：——

  公开号：US7745464B2

  公开（公告）日：2010-06-29
• US8372884B2
  申请人：——

  公开号：US8372884B2

  公开（公告）日：2013-02-12