3-imino-4-(4'-methoxyphenyl)-1,2,5-thiadiazolidine 1,1-dioxide | 141542-12-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-imino-4-(4'-methoxyphenyl)-1,2,5-thiadiazolidine 1,1-dioxide
• 英文别名: 4-(4-Methoxyphenyl)-4,5-dihydro-1,2,5-thiadiazol-3-amine 1,1-dioxide；3-(4-methoxyphenyl)-1,1-dioxo-2,3-dihydro-1,2,5-thiadiazol-4-amine
• CAS: 141542-12-3
• 化学式: C₉H₁₁N₃O₃S
• mdl: MFCD08444264
• 分子量: 241.271
• InChiKey: UOTYWJUVELGPDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.222
• 拓扑面积：
  102
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  sodium cyanide 、 4-甲氧基苯甲醛 在 磺酰胺 作用下， 反应 0.04h， 以95%的产率得到3-imino-4-(4'-methoxyphenyl)-1,2,5-thiadiazolidine 1,1-dioxide
  参考文献：
  名称：

  Microwave-Assisted Synthesis of Some Substituted Sulfamides

  摘要：

  Microwave-assisted synthesis of some substituted open-chain and cyclic sulfamides, by amine-exchange reaction, was studied in a modified domestic microwave oven. Reaction times and yields under microwave radiation were compared with classical heating. Synthesis of the sulfamides under microwave irradiation gave better yields with the desired compounds, and in considerably reduced reaction times, than those obtained by classical heating. [Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional figures.]

  DOI：

  10.1080/10426507.2013.819868

文献信息

• 3-Oxo- and 3-imino-4-substituted-1,2,5-thiadiazolidine 1,1-dioxides: synthesis, spectral properties, and selected chemistry
  作者：Chai Ho Lee、James D. Korp、Harold Kohn

  DOI：10.1021/jo00274a023

  日期：1989.6
• LEE, CHAI-HO;KORP, JAMES D.;KOHN, HAROLD, J. ORG. CHEM., 54,(1989) N3, C. 3077-3083
  作者：LEE, CHAI-HO、KORP, JAMES D.、KOHN, HAROLD

  DOI：——

  日期：——
• Microwave-Assisted Synthesis of Some Substituted Sulfamides
  作者：Aliye Gediz Erturk、Yunus Bekdemir

  DOI：10.1080/10426507.2013.819868

  日期：2014.1.1

  Microwave-assisted synthesis of some substituted open-chain and cyclic sulfamides, by amine-exchange reaction, was studied in a modified domestic microwave oven. Reaction times and yields under microwave radiation were compared with classical heating. Synthesis of the sulfamides under microwave irradiation gave better yields with the desired compounds, and in considerably reduced reaction times, than those obtained by classical heating. [Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional figures.]