2-[[2-azaniumyl-5-(diaminomethylideneazaniumyl)pentanoyl]amino]pentanedioate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[[2-azaniumyl-5-(diaminomethylideneazaniumyl)pentanoyl]amino]pentanedioate
• 化学式: C11H21N5O5
• 分子量: 303.32
• InChiKey: HFKJBCPRWWGPEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  194
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• Nutrient compositions
  申请人：The Montefiore Hospital Association of Western Pennsylvania

  公开号：EP0182356A2

  公开（公告）日：1986-05-28

  A nutrient composition includes at least two oligopeptides of amino acids having in the N-terminal position of at least one oligopeptide a residue of glycine and having in the N-terminal position of at least one oligopeptide a residue of L-alanine, L-lysine or L-arginine. The aqueous compositions may also contain free amino acids and may contain other nutrient substances such as fats, oligosaccharides, minerals, trace elements, vitamins and free amino acids. The compositions are intended for oral or parenteral use with mammals. Compositions having dipeptide concentrations higher than prior art compositions are disclosed. Compositions containing elevated concentrations of total protein greater than heretofor proposed employ both the described oligopeptides and also free amino acids.

  一种营养组合物包括至少两种氨基酸寡肽，其中至少一种寡肽的 N 端位置有甘氨酸残基，至少一种寡肽的 N 端位置有 L-丙氨酸、L-赖氨酸或 L-精氨酸残基。水性组合物还可能含有游离氨基酸，并可能含有其他营养物质，如脂肪、低聚糖、矿物质、微量元素、维生素和游离氨基酸。组合物用于哺乳动物的口服或肠道外使用。已公开的组合物的二肽浓度高于现有技术组合物。总蛋白质浓度高于现有技术的组合物既采用了所述的低聚肽，也采用了游离氨基酸。
• US5034377A
  申请人：——

  公开号：US5034377A

  公开（公告）日：1991-07-23
• [EN] NUTRITIVE POLYPEPTIDES, FORMULATIONS AND METHODS FOR TREATING DISEASE AND IMPROVING MUSCLE HEALTH AND MAINTENANCE<br/>[FR] POLYPEPTIDES NUTRITIFS, FORMULATIONS ET PROCÉDÉS POUR TRAITER DES MALADIES ET AMÉLIORER LA SANTÉ ET L'ENTRETIEN MUSCULAIRE
  申请人：PRONUTRIA INC

  公开号：WO2014134225A2

  公开（公告）日：2014-09-04

  Nutritive polypeptides are provided herein. Also provided are various other embodiments including pharmaceutical formulations containing the nutritive polypeptides, nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions that comprise the polypeptides, and methods of using the polypeptides to treat or prevent diseases, disorders and conditions associated with muscle wasting, and of using the polypeptides to improve and maintain muscle health.