N,N-dihexyl-tert-butoxycarbonylamide | 1062676-23-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N-dihexyl-tert-butoxycarbonylamide
• 英文别名: tert-butyl N,N-dihexylcarbamate
• CAS: 1062676-23-6
• 化学式: C₁₇H₃₅NO₂
• 分子量: 285.47
• InChiKey: GEBMBLYZBIIJPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N,N-dihexyl-4-methylbenzenesulfonamide 在 potassium diphenylphosphine 、 sodium hydroxide 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 14.5h， 生成 N,N-dihexyl-tert-butoxycarbonylamide
  参考文献：
  名称：

  芳基磺酰胺与磷阴离子在氮上的亲核取代反应

  摘要：

  已经描述了通过磷化物阴离子在芳基磺酰胺的氮上进行的新型亲核取代反应。该反应允许将芳基磺酰胺有效转化为具有合成价值的磷酰胺、胺和各种受保护的胺。

  DOI：

  10.1021/ja309642r

文献信息

• Sustainable and chemoselective N-Boc protection of amines in biodegradable deep eutectic solvent
  作者：Najmedin Azizi、Fatemeh Shirdel

  DOI：10.1007/s00706-016-1856-x

  日期：2017.6

  A green and practical approach for the chemoselective N-tert-butyloxycarbonylation of structurally diverse amines with di-tert-butyl dicarbonate (Boc(2)O) is described. Selective N-Boc protection was achieved in excellent yields in urea-choline chloride deep eutectic solvent (DES) as the most promising environmentally benign and cost-effective solvent under mild reaction condition. DES can protect various aromatic and aliphatic amines using Boc(2)O in good to excellent yields in short reaction times without any side products.
• PHOTOACID GENERATORS FOR EXTREME ULTRAVIOLET LITHOGRAPHY
  申请人：Glodde Martin

  公开号：US20090176175A1

  公开（公告）日：2009-07-09

  A photoacid generator P + A − comprises (a) an antenna group P + comprising atoms with high EUV photoabsorption cross-sections according to FIG. 1 and A − anions; or (b) an antenna group P + and A − comprising anions with low photoabsorption cross-sections for EUV; or (c) an antenna group P + , comprising atoms with high EUV photoabsorption cross-sections according to FIG. 1 and A − comprising anions with low photoabsorption cross-sections for EUV. Novel compounds comprise DTFPIO PFBuS, and DTBPIO CN5.
• Photoacid Generators for Extreme Ultraviolet Lithography
  申请人：Glodde Martin

  公开号：US20110143099A1

  公开（公告）日：2011-06-16

  A photoacid generator P + A − comprises (a) an antenna group P + comprising atoms with high EUV photoabsorption cross-sections according to FIG. 1 and A − anions; or (b) an antenna group P + and A − comprising anions with low photoabsorption cross-sections for EUV; or (c) an antenna group P + , comprising atoms with high EUV photoabsorption cross-sections according to FIG. 1 and A − comprising anions with low photoabsorption cross-sections for EUV. Novel compounds comprise DTFPIO PFBuS, and DTBPIO CN5.
• US8039194B2
  申请人：——

  公开号：US8039194B2

  公开（公告）日：2011-10-18
• US8652712B2
  申请人：——

  公开号：US8652712B2

  公开（公告）日：2014-02-18